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Now showing items 11-20 of 42
Evaluating the impact of critical product quality attributes on patient outcomes in biologics
(Massachusetts Institute of Technology, 2019)
The primary goal of this project is to link critical product quality attributes in biological medicines with patient outcomes as evidenced by clinical trial data. This project adopts a novel methodology of applying statistical ...
Reducing inventory through supply chain coordination and improved lead times
(Massachusetts Institute of Technology, 2020)
In supply chain management, it is commonly held that reducing lead times and minimum order quantities (MOQs) from suppliers can drive down the customer's inventory levels substantially. Customers providing a consumption ...
Next generation commercial aircraft engine maintenance, repair, and overhaul capacity planning and gap analysis
(Massachusetts Institute of Technology, 2018)
A critical element in maintaining engine safety and in providing post-production service and support of a commercial aircraft engine is the complete worldwide network of maintenance, repair, and overhaul facilities. Matching ...
Inbound supply chain optimization with ship-mode variation in a fixed-capacity fulfillment center
(Massachusetts Institute of Technology, 2018)
each of the past two years. In order to scale with expected continued sales growth, Amazon has been investing heavily in its inbound supply chain, where product is received and allocated to various nodes, with cross-dock ...
Improving lead time setting and on-time delivery commitments under uncertain supply conditions
(Massachusetts Institute of Technology, 2018)
As Dell seeks to continually improve customer experience, the company is identifying new and innovative ways to improve on-time delivery. Inventory shortages that occur prior to production account for approximately 35% of ...
Development of a tool for forecasting a warehouse facility footprint and enabling rapid scenario analysis
(Massachusetts Institute of Technology, 2010)
Companies in every industry, including both manufacturers and service providers, must make decisions about their operational footprint -the amount of building space required for business needs such as storing inventory and ...
Implementing change through a supplier evaluation process
(Massachusetts Institute of Technology, 2010)
With increased global competition, companies find that they must adjust and adapt to a supply chain model that incorporates more strategic suppliers. Pratt & Whitney, a division of United Technology Corporation, is no ...
Predicting corrosion on protected buried steel natural gas distribution pipelines
(Massachusetts Institute of Technology, 2015)
PG&E uses cathodic protection, which connects the pipeline to sacrificial anodes that corrode instead of the pipeline, to prevent corrosion on its buried steel natural gas pipelines. However, corrosion leaks still occur. ...
Disaggregation of residential home energy via non-intrusive load monitoring for energy savings and targeted demand response
(Massachusetts Institute of Technology, 2018)
Residential energy disaggregation is a process by which the power usage of a home is broken down into the consumption of individual appliances. There are a number of different methods to perform energy disaggregation, from ...
Establishing an inventory management process to meet high customer service levels in a vaccines organization
(Massachusetts Institute of Technology, 2010)
Inventory management is a complex aspect of Supply Chain Management that is frequently discussed and debated due to the fact that it has a high impact on customer satisfaction as well as financial performance. This thesis ...