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Now showing items 11-20 of 510
Value of distribution-level reactive power for combined heat and power systems
(Massachusetts Institute of Technology, 2020)
As the U.S. electric grid continues to experience an increase in the penetration of distributed energy resources (DER), electric utilities are evaluating new approaches for utilizing DER to help cost-effectively maintain ...
Optimizing inbound freight mode decisions
(Massachusetts Institute of Technology, 2020)
Retail manufacturers often expedite inbound freight shipments from contract manufacturing bases to their distribution centers in destination markets at high cost to improve service levels to their wholesale partners and ...
Artificial intelligence infrastructure into material attributes insights
(Massachusetts Institute of Technology, 2020)
The development of a biopharmaceutical manufacturing process involves an assessment of all possible sources of variation throughout each of the unit operations in the drive toward six sigma manufacturing. The primary goal ...
Evaluating modeling techniques for quantifying production risk in contact lens manufacturing
(Massachusetts Institute of Technology, 2020)
Johnson & Johnson Vision (JJV) is a leading manufacturer of contact lenses offering a variety of vision correction products. They have a strong commitment to innovation--defining new product categories and improving existing ...
Commercial technology transfer optimization for drug substance process development
(Massachusetts Institute of Technology, 2019)
Commercial technology transfer for biopharmaceuticals is the process of transferring process and product knowledge between process development and manufacturing organizations to achieve product realization. This process ...
Implementation of automated visual inspection machines in biopharmaceutical industry
(Massachusetts Institute of Technology, 2019)
Currently, manual visual inspection is the gold standard for the required visual inspection of particulate matter in parenteral medicines. Automated visual inspection machines offer an opportunity for Amgen to improve ...
Investigating the feasibility and impact of integrating wire-arc additive manufacturing in aerospace tooling applications
(Massachusetts Institute of Technology, 2020)
The use of wire-arc additive manufacturing (WAAM) as fabrication method for Iron-Nickel 36 (Invar36) alloy aerospace tooling is a growing area of interest for many tooling companies and composite aircraft manufacturers. ...
Applications of risk pooling for the optimization of spare parts with stochastic demand within large scale networks
(Massachusetts Institute of Technology, 2020)
Amazon is able to deliver millions of packages to customers every day through its Fulfillment Center (FC) network that is powered by miles of material handling equipment (MHE) such as conveyor belts. Unfortunately, this ...
Optimizing thermal spray quality verification in FAA repair station specializing in rotating components
(Massachusetts Institute of Technology, 2020)
Thermal spray is a manufacturing process where melted particles are sprayed onto a surface to build up thickness. It is used extensively in the aerospace industry to improve and repair part surfaces, extending the useful ...
Process Intensification of Spodoptera frugiperda (Sf) Cell Growth via Multi-Parallel Bioreactor System
(Massachusetts Institute of Technology, 2020)
The objective of this project is to improve the yield of the fed-batch manufacturing process for the production of Flublok influenza vaccine, which was approved by the FDA in 2018. In short, Spodoptera frugiperda (SF+) ...