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Now showing items 11-20 of 27
A framework for analyzing biopharmaceutical product introduction in an emerging market
(Massachusetts Institute of Technology, 2006)
Biopharmaceutical companies are under constant pressure to deliver double-digit growth. In traditional markets such as the U.S., Japan, and the European Union growth is stagnant, and profit margins are falling due to ...
Integrating cost consequences into a high quality manufacturing environment
(Massachusetts Institute of Technology, 2003)
Intel Corporation, the world leader in manufacturing microprocessors, has beer successful in achieving high margins because of its ability to successfully deliver high volume and reliable microprocessors at high demand. ...
Analysis of variability in the semiconductor industry
(Massachusetts Institute of Technology, 2004)
While the pace of technical innovation in the semiconductor industry continues to accelerate, business processes and supply chain techniques have not kept up. Microprocessor performance improvement continues to follow ...
Implementation of new technology in a regulated environment
(Massachusetts Institute of Technology, 2004)
This thesis investigates potential improvements to the manufacturing process through the implementation of process analytical technologies (PAT) in the heavily regulated pharmaceutical industry. The thesis focuses on the ...
A comparative analysis of diagnostic tools and techniques for manufacturing business support
(Massachusetts Institute of Technology, 2004)
The overriding objective of diagnostic assessment is change. Assessment processes are a mechanism to identify areas that merit change. In order to maximize the possibility that a company will adopt recommended changes ...
Batch sizing strategy & production load leveling in a multi-step chemical manufacturing process
(Massachusetts Institute of Technology, 2005)
In the last couple of years Eastman Kodak Company went through major changes in its strategic direction. The same disruptive technologies that they helped develop for digital imaging have shaped a new industry, and the ...
Optimization of preclinical profiling operations in drug discovery
(Massachusetts Institute of Technology, 2007)
In early-stage drug discovery, thousands of compounds must be tested using in vitro assays to determine their exposure and safety characteristics. This data is used to guide the selection of potential drug candidates and ...
Operations capability improvement of a molecular biology laboratory in a high throughput genome sequencing center
(Massachusetts Institute of Technology, 2005)
The Broad Institute is a research collaboration of MIT, Harvard University and affiliated hospitals, and the Whitehead Institute for Biomedical Research. Its scientific mission is to "(1) create tools for genomic medicine ...
Analyzing and improving throughput of Automated Storage and Retrieval Systems in personal computer manufacturing
(Massachusetts Institute of Technology, 2005)
The content of this thesis draws heavily on work completed during a 6.5 month MIT Leaders for Manufacturing (LFM) internship at Dell Corporation's personal computer manufacturing facility in Lebanon, Tennessee (EG1) from ...
A short-range forecasting and inventory strategy for new product launches
(Massachusetts Institute of Technology, 2005)
Companies like Procter & Gamble that operate on a make-to-stock strategy use forecasts to drive their manufacturing, selling, and buying processes. Because forecasting future demand is not an exact science, inventory ...