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Now showing items 191-200 of 200
Developing biotechnology company's future positioning strategy in prefilled syringe market
(Massachusetts Institute of Technology, 2010)
The primary goal for the thesis is to develop a recommendation for Amgen's future prefilled syringe strategy related to its drug process development, supplier relationship management plan, supply and sourcing, and procurement. ...
Understanding and managing profitability in a competitive environment : an application in biotechnology
(Massachusetts Institute of Technology, 2010)
For many biotech drugs, minimal competition has led to significant margins. Genentech's legacy product, however, faces intense competition from six other competitors. Competition necessitates contracting to ensure patient ...
Modeling drug substance purification manufacturing through schedule optimization and simulation
(Massachusetts Institute of Technology, 2017)
This thesis develops a method by which overtime could be reduced in a highly variable drug substance purification manufacturing environment. Purification production overtime (20%) is a big cost driver at Building XX1 (BXX). ...
Enabling effective lifecycle management of manufacturing facilities with enhanced decision making processes
(Massachusetts Institute of Technology, 2017)
As a global manufacturing company, Company X has built up an extensive and varied portfolio of manufacturing facilities. These facilities vary greatly in capability, age, and performance. This creates difficulties in ...
Continuous improvement of occupational safety performance in aerospace production systems through collaborative automation
(Massachusetts Institute of Technology, 2016)
Employee health and safety are a top priority in aerospace manufacturing. As companies increase their production systems capacity in preparation for upcoming rate targets, new opportunities for continuous improvement start ...
Rapid supply chain strategy simulation development for enhanced cross-functional collaboration in high growth environments
(Massachusetts Institute of Technology, 2016)
Like companies from almost every industry, NIKE faces a marketplace that is transitioning toward e-commerce. Over the next five years, retail sales through NIKE.com are anticipated to grow meteorically. For NIKE specifically, ...
Artificial intelligence opportunities and an end-do-end data-driven solution for predicting hardware failures
(Massachusetts Institute of Technology, 2016)
Dell's target to provide quality products based on reliability, security, and manageability, has driven Dell Inc. to become one of the largest PC suppliers. The recent developments in Artificial Intelligence (AI) combined ...
Analysis of a diagnostics firm's pre-analytical processes
(Massachusetts Institute of Technology, 2016)
Quest Diagnostics provides diagnostic information to clinicians, allowing them to make informed decisions on the appropriate course of treatment for their patients. Quest advertises an 8 a.m. next-day turnaround time for ...
Container removal and replacement automation : design and development of robotic work cells for warehouse automation
(Massachusetts Institute of Technology, 2019)
Amazon has grown at a rapid pace. In 2018, Amazon retail sales amounted to $141.92B, up 19.7% from the previous year. The number of units shipped through its Prime program alone grew by 20% from 5 billion the previous year ...
Project-based manufacturing : an approach for quote development
(Massachusetts Institute of Technology, 2020)
Project-based manufacturing presents unique challenges that highly automated and repetitive production lines do not face. Highly automated production lines do not have much variation in the types of products that are made, ...