Search
Now showing items 41-46 of 46
Developing a use case for implementing modular engineering at portfolio companies
(Massachusetts Institute of Technology, 2018)
Modular engineering allows the creation of a product architecture that prepares the product families of companies for a fast response to changes in technology and customer demand. This thesis will focus on developing and ...
Enhancing the design and procurement of single-use assemblies in biomanufacturing by implementing modular specifications
(Massachusetts Institute of Technology, 2018)
Usage of single-use systems (SUS) in biomanufacturing has expanded rapidly in recent years. Amgen uses SUS at several commercial manufacturing sites, in addition to pilot plants and clinical production. Each single-use ...
Long range planning of manufacturing footprint
(Massachusetts Institute of Technology, 2018)
Firms developing an Operations Strategy need to make decisions across a wide spectrum. Within the field of operations strategy, common practice defines the stratification of these decisions into structural and infrastructural ...
Prediction and prevention of the bullwhip effect in replenishment supply chains
(Massachusetts Institute of Technology, 2018)
Nikes replenishment supply chain stages finished goods and materials at distribution centers and factories to provide short replenishment lead times to customers. Make-to-stock supply chains are particularly susceptible ...
Predictive earthquake damage modeling for natural gas distribution infrastructure
(Massachusetts Institute of Technology, 2018)
The Pacific Gas and Electric Company (PG&E) operates and maintains 48,000 miles of natural gas pipeline, serving over 4.3 million customer accounts. Along with water, electric power, and transportation services, these ...
Oral drug delivery as an alternative to needle-based injection for large molecules : an assessment of the field & evaluation of high-priority technologies
(Massachusetts Institute of Technology, 2018)
Oral delivery of large molecules is widely considered the "holy grail" of drug delivery, but attempts to achieve this within the past century have been met with a lack of success, confounded by low bioavailability. Novel ...