Search
Now showing items 1-10 of 15807
Investigating the mechanotransduction by two-photon fluorescence microscopy measurement of intracellular free energy of binding
(Massachusetts Institute of Technology, 2008)
Force, due either to haemodynamic shear stress or relayed directly to the cell through adhesion complexes, is transmitted and translated into biological signals. This process is known as mechanotransduction. Extensive ...
Enabling effective product launch decisions
(Massachusetts Institute of Technology, 2008)
The present work looks into the question of optimizing the performance of product launch decisions-in particular, the decisions of product development duration and manufacturing ramp-up. It presents an innovative model for ...
A continuum model for needlepunched nonwoven fabrics
(Massachusetts Institute of Technology, 2008)
Nonwoven fabrics are sheet structures created by bonding or interlocking a web (network) of fibers through mechanical, thermal or chemical processes. In general, the mechanical response of nonwoven fabrics exhibits two ...
Microstructurally-based constitutive models of cytoskeletal networks for simulation of the biomechanical response of biological cells
(Massachusetts Institute of Technology, 2008)
The elastic and viscoelastic stress-strain behavior of cytoskeletal networks, important to many cellular functions, is modeled via a microstructurally-informed continuum mechanics approach. The force-extension behavior of ...
Physics and learning based computational models for breaking bow waves based on new boundary immersion approaches
(Massachusetts Institute of Technology, 2008)
A ship moving on the free surface produces energetic breaking bow waves which generate spray and air entrainment. Present experimental, analytic, and numerical studies of this problem are costly, inaccurate and not robust. ...
An investigation of the structure-function relationship in human cervical tissue
(Massachusetts Institute of Technology, 2008)
The cervix plays a crucial role in maintaining a healthy pregnancy, acting as a mechanical barrier to hold the fetus inside the uterus during gestation. Altered biochemical and mechanical properties of the cervical tissue ...
Three-dimensional object registration using wavelet features
(Massachusetts Institute of Technology, 2008)
Recent developments in shape-based modeling and data acquisition have brought three-dimensional models to the forefront of computer graphics and visualization research. New data acquisition methods are producing large ...
Effect of loading history in necking and fracture
(Massachusetts Institute of Technology, 2008)
The effect of Lode angle parameter, or the third deviatoric stress invariant, on plasticity and fracture is studied using flat-grooved transverse plane strain specimens. A generalized asymmetric plasticity model for isotropic ...
Variation analysis of cold rolled steel manufacturing
(Massachusetts Institute of Technology, 2000)
Mixture preparation behavior in port fuel injected spark ignition engines during transient operation
(Massachusetts Institute of Technology, 2000)