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Multi-mode two-dimensional infrared spectroscopy of peptides and proteins 

DeFlores, Lauren P (Massachusetts Institute of Technology, 2008)
In this thesis, a methodology for understanding structural stability of proteins through multi-mode two-dimensional infrared (2D IR) spectroscopy is developed. The experimental framework for generation of broadband infrared ...
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Mechanistic investigation of coordinated conformational changes in multisubunit ion channels and enzymes 

Choi, Kee-Hyun (Massachusetts Institute of Technology, 2008)
Many enzymes and ion channels consist of multiple subunits and/or multiple distinct functional components. Coordinated conformational changes through allosteric interactions between subunits and/or between functional units ...
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Studies directed towards the total synthesis of (+)-sieboldine A 

Gehling, Victor S. (Victor Scott) (Massachusetts Institute of Technology, 2008)
Progress towards the total synthesis of sieboldine A is described. This synthetic approach uses a nickel-catalyzed alkyne-ketone reductive cyclization to form the hydrindane core of the natural product in good yield and ...
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The detection of nitric oxide and its reactivity with transition metal thiolate complexes 

Tennyson, Andrew Gregory (Massachusetts Institute of Technology, 2008)
Nitric oxide (NO) is a molecule that is essential for life and regulates both beneficial and harmful processes. Because this gaseous radical influences many aspects of health and disease, we wish to explore the relationship ...
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Polymers containing calix[4]arenes and triptycenes : new syntheses, properties and applications 

Yang, Yong, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2008)
This thesis details the development of new synthetic methods for making polymers with complex molecular structures. Calix[4]arenes and triptycenes are the two major molecular building blocks for constructing the functional ...
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Observing the unfolding transition of [beta]-hairpin peptides with nonlinear infrared spectroscopy 

Smith, Adam Wilcox, 1977- (Massachusetts Institute of Technology, 2008)
The biological function of a protein is in large measure determined by its three-dimensional structure. To date, however, the transition of the protein between the native and non-native conformations is not well-understood. ...
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Development and assessment of a soot emissions model for aircraft gas turbine engines 

Martini, Bastien (Massachusetts Institute of Technology, 2008)
Assessing candidate policies designed to address the impact of aviation on the environment requires a simplified method to estimate pollutant emissions for current and future aircraft gas turbine engines under different ...
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Entry, descent and landing vehicle design space exploration for crewed Mars missions 

Khan, Zahra (Massachusetts Institute of Technology, 2008)
With the announcement of the Vision for Space Exploration in 2004, NASA has been preparing plans for a crewed mission to Mars in the next few decades. One challenge associated with crewed missions to the Martian surface ...
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The nanogranular origin of concrete creep : a nanoindentation investigation of microstructure and fundamental properties of calcium-silicate-hydrates 

Vandamme, Matthieu (Massachusetts Institute of Technology, 2008)
With an annual per capita consumption of one cubic meter, concrete is the most manufactured material on Earth. But concrete subject to sustained load creeps, like chewing gum, at a rate that deteriorates the durability and ...
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Colloidal semiconductor nanocrystals as nanoscale emissive probes in light emitting diodes and cell biology 

Huang, Hao, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2008)
This thesis employs colloidal semiconductor nanocrystals (NCs) as nanoscale emissive probes to investigate the physics of light emitting diodes (LEDs), as well as to unveil properties of cells that conventional imaging ...
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AuthorChen, Yi (2)Hagan, William L. (William Laurie), III (2)He, Ruijie (2)Israelsson, Peter H. (Peter Hampus), 1973- (2)Jafarpour, Behnam (2)Larsen, Erik (2)Abadi, Daniel J. (1)Abanin, Dmitry A (1)Abbe, Emmanuel Auguste (1)Abbott, Timothy Good (1)... View MoreDepartmentDepartment of Electrical Engineering and Computer Science (337)Department of Mechanical Engineering (275)Department of Urban Studies and Planning (99)Sloan School of Management (97)Engineering Systems Division (94)Department of Aeronautics and Astronautics (90)Department of Architecture (90)Department of Materials Science and Engineering (90)Department of Civil and Environmental Engineering (78)Department of Physics (74)... View MoreDegreePh.D. (592)S.M. (574)M.Eng. (217)S.B. (197)M.C.P. (68)M.B.A. (59)S.M.in Real Estate Development (32)M.Arch. (27)M.Eng.in Logistics (24)Nav.E. (7)... View MoreSubjectElectrical Engineering and Computer Science. (337)Mechanical Engineering. (276)Urban Studies and Planning. (98)Aeronautics and Astronautics. (90)Architecture. (90)Materials Science and Engineering. (90)Engineering Systems Division. (84)Civil and Environmental Engineering. (77)Sloan School of Management. (75)Physics. (73)... View MoreDate Issued
2008 (1776)
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