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Commercial technology transfer optimization for drug substance process development
(Massachusetts Institute of Technology, 2019)
Commercial technology transfer for biopharmaceuticals is the process of transferring process and product knowledge between process development and manufacturing organizations to achieve product realization. This process ...
Implementation of automated visual inspection machines in biopharmaceutical industry
(Massachusetts Institute of Technology, 2019)
Currently, manual visual inspection is the gold standard for the required visual inspection of particulate matter in parenteral medicines. Automated visual inspection machines offer an opportunity for Amgen to improve ...
Using data science and model based systems engineering to design and operate production systems
(Massachusetts Institute of Technology, 2019)
Over the last several decades, products and the production systems within the aerospace industry have grown increasingly complex --
Life-cycle cost modeling and Optimization for capital equipment procurement
(Massachusetts Institute of Technology, 2019)
Composite airplane manufacturing requires the use of autoclaves to cure composite materials in order to create durable, lightweight parts for use in airplanes. The large size, complexity and utility consumption of this ...
Using factory-level digital tools to improve quality and productivity in garment factories
(Massachusetts Institute of Technology, 2019)
The retail landscape is rapidly changing as evolving consumer habits are resulting in smaller batch quantities and shorter lead times, requiring Li & Fung to have a more digitally connected, nimble vendor base. Li & Fung ...
Value proposition analysis for medium- and heavy- lift cargo unmanned aircraft systems
(Massachusetts Institute of Technology, 2019)
The majority of current unmanned aircraft system (UAS) research is focusing on small UAS operations at low altitude over rural and underpopulated areas. There is a gap in research about UAS greater than 55 pounds. The first ...
External risk monitoring and inventory sizing in supply chain disruption mitigation
(Massachusetts Institute of Technology, 2019)
As AstraZeneca's product portfolio becomes increasingly complex, its supply chains must evolve in parallel. These supply chains operate in an environment of ever-present external risks such as factory fires, geopolitical ...
Predicting competitor restructuring using machine learning methods
(Massachusetts Institute of Technology, 2019)
Increasing competition in the defense industry risks contract margin degradation and increases the need for new avenues to margin expansion. One such area of opportunity is take-away bids for under-performing competitor ...
Analysis of robotic systems test methods targeting test resource utilization improvement
(Massachusetts Institute of Technology, 2019)
The robotics industry continues to grow rapidly. More industries are moving towards automation and are looking for the robotics industry to support the industry 4.0 movement. Due to a push by consumers, robotics producers ...
Development of a connected platform for industrial equipment monitoring to enable predictive maintenance using supervised machine learning methods
(Massachusetts Institute of Technology, 2019)
SHAPE Technologies is the world leader in ultra high pressure industrial waterjet systems for cutting and cleaning with applications from metal to food. Although SHAPE is the technological leader in this space, SHAPE must ...