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Biodegradable microfluidic scaffolds for vascular tissue engineering
(Massachusetts Institute of Technology, 2004)
This work describes the integration of novel microfabrication techniques for vascular tissue engineering applications in the context of a novel biodegradable elastomer. The field of tissue engineering and organ regeneration ...
Murine embryonic stem cells and hypoxia : growth kinetics, metabolism, and plating efficiency
(Massachusetts Institute of Technology, 2004)
There is reason to believe that embryonic stem cells would grow favorably in a hypoxic environment. These cells come from the pre-implantation embryo, whose native environment is the hypoxic mammalian reproductive tract. ...
Fundamental differentiation and growth characterization of murine embryonic stem cells in varied culture conditions
(Massachusetts Institute of Technology, 2004)
Although embryonic stem (ES) cells and their pluripotent capability have been elucidated for decades, little study has been done on obtaining the pluripotency profile of ES cells in the incipient stages of differentiation. ...
Use of gene expression to characterize heterogeneous liver cell populations
(Massachusetts Institute of Technology, 2004)
Non-parenchymal cells (NPC's) are integral to recreate the native hepatic microenvironment and necessary to maintain in vivo liver function. A variety of in vitro culture systems have been developed to address different ...
Characterization of self-assembling peptide nanofibers of KLD12 and RID 12
(Massachusetts Institute of Technology, 2004)
Self-assembling peptides are a promising new area of research with usage in numerous areas, from tissue engineering to membrane protein biology. This work is to further study the characteristics of the peptides KLD12 and ...
Development of a biocompatible method of implanting multi-electrode arrays for stable chronic deep neuronal recording
(Massachusetts Institute of Technology, 2004)
(cont.) electrodes.
Measuring mechanical properties of the tectorial membrane with a microfabricated probe
(Massachusetts Institute of Technology, 2004)
Dynamic material properties of the isolated mouse tectorial membrane (TM) were quantified by applying sinusoidal shearing forces to the TM with a microfabricated probe (contact area 30 x 30 [micro]m²). Forces in the range ...
The applications of comb polymer to the study of liver cell adhesion and signaling
(Massachusetts Institute of Technology, 2004)
Comb polymer, which consists of a hydrophobic poly(methyl methacrylate) (PMMA) backbone with hydrophilic hydroxy-poly(ethylene oxide) (HPOEM) side chains, is a tool that has many possible applications for the study of liver ...