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Antibody drug discovery: From Idea to Biotherapeutic Molecule
(Massachusetts Institute of Technology, 2016)
Graybel (a fictitious name used for privacy reasons) is a large developer of pharmaceuticals. Graybel's Antibody Protein Engineering Group (APEG) is responsible for early stage drug development of biotherapeutic molecules. ...
Routine Post-Procedure Recovery (RPPR) patients at Massachusetts General Hospital
(Massachusetts Institute of Technology, 2016)
This project offers improved strategies for managing the flow of surgical patients who are categorized as Routine Post-Procedure Recovery (RPPR) in Massachusetts General Hospital (MGH). Strategies were developed by analyzing ...
Production leveling and cycle time reduction in satellite manufacturing
(Massachusetts Institute of Technology, 2016)
Reducing cycle time for geostationary communication satellites represents a major competitive advantage for manufacturers. Reducing cycle time can be done through application of lean manufacturing techniques such as ...
Convenient truths : empowering employees, empowering energy choices
(Massachusetts Institute of Technology, 2016)
Journey Health is an industry leader in medical testing, touching a large portion of Americans each year. To maintain this position, the company makes strategic investments in R&D, business development, and continuous ...
Managing expectations during acquisition of bespoke automation systems
(Massachusetts Institute of Technology, 2016)
A new facility seeks to manufacture inlets for the turbine of the new NDA aircraft. The inlet is a new design and has never been built before. To complicate matters the manufacturer, Aeron 2 Company, has not traditionally ...
Production of AAV vectors for gene therapy : a cost-effectiveness and risk assessment
(Massachusetts Institute of Technology, 2016)
Gene therapy is a promising modality for the potential treatment of rare Mendelian diseases. To date a number of high profile proof-of-concept studies within the industry have demonstrated the significant disease-correcting ...
Amazon UK transshipment stow process analysis through discrete event simulation
(Massachusetts Institute of Technology, 2016)
This thesis investigated Amazon's implementation of transshipment, the act of moving inventory between fulfillment centers to facilitate order fulfillment, inventory rebalancing, and operational cost reduction. The role ...
Environmental sustainability assessment tool for factories
(Massachusetts Institute of Technology, 2016)
General interest and international regulations have begun to create a world in which consumers demand to know how their products are made and companies must provide that transparency. With over 15,000 suppliers, Li & Fung ...
Continuous improvement of occupational safety performance in aerospace production systems through collaborative automation
(Massachusetts Institute of Technology, 2016)
Employee health and safety are a top priority in aerospace manufacturing. As companies increase their production systems capacity in preparation for upcoming rate targets, new opportunities for continuous improvement start ...
Rapid supply chain strategy simulation development for enhanced cross-functional collaboration in high growth environments
(Massachusetts Institute of Technology, 2016)
Like companies from almost every industry, NIKE faces a marketplace that is transitioning toward e-commerce. Over the next five years, retail sales through NIKE.com are anticipated to grow meteorically. For NIKE specifically, ...