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Capacity analysis, cycle time optimization, and supply chain strategy in multi-product biopharmaceutical manufacturing operations
(Massachusetts Institute of Technology, 2011)
Application of system optimization theory, supply chain principles, and capacity modeling are increasingly valuable tools for use in pharmaceutical manufacturing facilities. The dynamics of the pharmaceutical industry - ...
Strategic development of a manufacturing execution system (MES) for cold chain management using information product mapping
(Massachusetts Institute of Technology, 2011)
The Vaccines & Diagnostics (V&D) division of Novartis recently developed a global automation strategy that highlights the need to implement a manufacturing execution system (MES). Benefits of an MES (electronic production ...
Feature-based investment cost estimation based on modular design of a continuous pharmaceutical manufacturing system
(Massachusetts Institute of Technology, 2011)
Previous studies of continuous manufacturing processes have used equipment-factored cost estimation methods to predict savings in initial plant investment costs. In order to challenge and validate the existing methods of ...
Development of operations based long range network capacity planning models
(Massachusetts Institute of Technology, 2011)
Planning for vaccines manufacturing capacity is both a complex task requiring many inputs and an important function of manufacturers to ensure the supply of vaccines that prevent life-threatening illnesses. This thesis ...