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Predicting department of medicine inpatients' discharges at US hospitals
(Massachusetts Institute of Technology, 2018)
In the last few years, US hospitals have faced severe challenges with bed capacity management that leads to capacity congestion. Delivering patients to the right bed at the right time is very important to patient care ...
Simulation and optimization of outbound operations in an e-grocer's warehouse
(Massachusetts Institute of Technology, 2018)
A second wave of online grocery retailers ("e-grocers") emerged in late 2000's after dot.com companies, such as Webvan, Streamline and Homegrocer, failed to break into the grocery market despite investing heavily on automated ...
Waveless picking : managing the system and making the case for adoption and change
(Massachusetts Institute of Technology, 2010)
Wave-based picking systems have been used as the standard for warehouse order fulfillment for many years. Waveless picking has emerged in recent years as an alternative pick scheduling system, with proponents touting the ...
Modeling the effects of advanced automation and process design on Cell Line Development
(Massachusetts Institute of Technology, 2015)
Research and development of biologic drugs is a time- and resource-intensive process that can span several years and billions of dollars. Any improvements in the efficiency and end-to-end cycle time of this process provide ...
Implementation of a manufacturing technology roadmapping initiative
(Massachusetts Institute of Technology, 2012)
Strategic technology planning is a core competency of companies using technological capabilities for competitive advantage. It is also a competency with which many large companies struggle due to the cross-functional ...
Congestion reduction in the Emergency Department of Massachusetts General Hospital
(Massachusetts Institute of Technology, 2018)
The MGH Emergency Department (ED) and General Medicine Floor currently experience heavy patient volume and rising patient wait times, despite recent capacity expansions. While several projects have been piloted to divert ...
Amazon UK transshipment stow process analysis through discrete event simulation
(Massachusetts Institute of Technology, 2016)
This thesis investigated Amazon's implementation of transshipment, the act of moving inventory between fulfillment centers to facilitate order fulfillment, inventory rebalancing, and operational cost reduction. The role ...
Virtual pooling approximation using longest path network optimization
(Massachusetts Institute of Technology, 2018)
Abstract This thesis proposes a network swapping mechanism to approximate a virtual finished goods inventory pool under the constraint of fragmented commercial channel ownership. Globally, Caterpillar sells its product ...
Modeling and economic evaluation of early stage clinical monoclonal antibody manufacturing using single use technology
(Massachusetts Institute of Technology, 2015)
A critical cost driver in the product development process is the manufacturing of clinical trial material supplies. The clinical manufacturing process operates under similar regulatory burdens as commercial biopharmaceutical ...
Deep learning for automated visual inspection of uncured rubber
(Massachusetts Institute of Technology, 2018)
This thesis proposes a data-driven approach to automate the visual inspection of uncured rubber tire assemblies. Images collected from a machine vision system are used to develop proof of concept predictive models to ...