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Assessing and reducing product portfolio complexity in the pharmaceutical industry
(Massachusetts Institute of Technology, 2011)
Overly complex product portfolios lead to inefficient use of resources and limit an organization's ability to react quickly to changing market dynamics. The challenges of reducing portfolio complexity are defining excess ...
Improving supply chain responsiveness for diesel engine remanufacturing
(Massachusetts Institute of Technology, 2011)
Achieving a significant reduction in order-to-shipment lead-time of remanufactured diesel engines can dramatically decrease the amount of finished goods inventory that Caterpillar needs to carry in order to meet its delivery ...
Value stream financial modeling for improved production decision making
(Massachusetts Institute of Technology, 2011)
Understanding the overall impact of a decision in a manufacturing system can be challenging given the complex production and financial structures in today's companies. While knowing the direct result of a local change may ...
Allocation strategy for production network designed to mitigate risk
(Massachusetts Institute of Technology, 2011)
Amgen Inc. currently manufactures, formulates and fills substantially all of their global drug product units in a single primary facility ("Site 1A"). Concerned about the inherent risks posed by the geographic concentration ...
Segmentation strategies for managing retail supply chains
(Massachusetts Institute of Technology, 2011)
High-technology manufacturing companies often face rapid price decline and capacity constraints. Especially in the retail side of the business where the supply chain is much longer and revenue is sometimes not recognized ...
Process management applications in biopharmaceutical drug production
(Massachusetts Institute of Technology, 2011)
Genzyme's manufacturing and supply chain organization is responsible for the production and delivery of medically necessary medicines for patients with rare diseases around the world. Because of the nature of the products ...
Competitive pricing and learning in CPU sockets
(Massachusetts Institute of Technology, 2011)
An Intel processor can be electrically attached to a PC motherboard permanently or via a component called a socket. Intel defines the critical interfaces between the socket and the processor. Independent suppliers then ...
Applying a MEIO approach to manage Intel's VMI Hub Supply
(Massachusetts Institute of Technology, 2011)
To improve customer service levels, Intel implemented Vendor Managed Inventory (VMI) hub process for its Central Processing Unit (CPU) Finished Good (FG) inventory, which allows Intel's customers to pull inventory directly ...
Analysis of predictive sorting and process standardization at Amazon.com
(Massachusetts Institute of Technology, 2011)
In any process, complexity has the potential to decrease processing rates of the operation. Mass production has driven up operator efficiency by removing complexity to create a standardized and simplified process. However, ...
A case study : creating momentum and self-sustaining change in product development through continuous improvement efforts
(Massachusetts Institute of Technology, 2011)
Traditionally, in Raytheon's Integrated Defense System Product Development Engineering Group, lean initiatives have not been fully adopted. Though the lean tools are useful, the engineering group is looking for more effective ...