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Implementation of automated visual inspection machines in biopharmaceutical industry
(Massachusetts Institute of Technology, 2019)
Currently, manual visual inspection is the gold standard for the required visual inspection of particulate matter in parenteral medicines. Automated visual inspection machines offer an opportunity for Amgen to improve ...
Investigating the feasibility and impact of integrating wire-arc additive manufacturing in aerospace tooling applications
(Massachusetts Institute of Technology, 2020)
The use of wire-arc additive manufacturing (WAAM) as fabrication method for Iron-Nickel 36 (Invar36) alloy aerospace tooling is a growing area of interest for many tooling companies and composite aircraft manufacturers. ...
Applications of risk pooling for the optimization of spare parts with stochastic demand within large scale networks
(Massachusetts Institute of Technology, 2020)
Amazon is able to deliver millions of packages to customers every day through its Fulfillment Center (FC) network that is powered by miles of material handling equipment (MHE) such as conveyor belts. Unfortunately, this ...
Optimizing thermal spray quality verification in FAA repair station specializing in rotating components
(Massachusetts Institute of Technology, 2020)
Thermal spray is a manufacturing process where melted particles are sprayed onto a surface to build up thickness. It is used extensively in the aerospace industry to improve and repair part surfaces, extending the useful ...
Process Intensification of Spodoptera frugiperda (Sf) Cell Growth via Multi-Parallel Bioreactor System
(Massachusetts Institute of Technology, 2020)
The objective of this project is to improve the yield of the fed-batch manufacturing process for the production of Flublok influenza vaccine, which was approved by the FDA in 2018. In short, Spodoptera frugiperda (SF+) ...
Benchmarking environmental efficiency of garment factories to understand the value of real-time environmental data
(Massachusetts Institute of Technology, 2020)
Li & Fung works with over 10,000 factories distributed across 50 countries to design, produce, and deliver hard- and soft- goods to over 2,000 apparel and consumer goods customers. An increasingly prevalent focus of the ...
Reducing inventory through supply chain coordination and improved lead times
(Massachusetts Institute of Technology, 2020)
In supply chain management, it is commonly held that reducing lead times and minimum order quantities (MOQs) from suppliers can drive down the customer's inventory levels substantially. Customers providing a consumption ...
A data-driven approach to continuous improvement in reverse logistics
(Massachusetts Institute of Technology, 2020)
Verizon may rely on third-party logistics providers (3PLs) to manage some aspects of the reverse supply chain of Fios equipment. As a result, it depends on the 3PL to continually strive for increased quality, reliability, ...
Cost of complexity : mitigating transition complexity in mixed-model assembly lines
(Massachusetts Institute of Technology, 2020)
The Nissan Smyrna automotive assembly plant is a mixed-model production facility which currently produces six different vehicle models. This mixed-model assembly strategy enables the production level adjustment of different ...
Floor entry task prioritization for highly automated fulfillment centers
(Massachusetts Institute of Technology, 2020)
As automation continues to gain prevalence within the retail industry, informed decision-making by users of robotic systems is critical for management of throughput and operating expenditures. On robotic fulfillment floors, ...