Now showing items 1-3 of 907

    • Synthetic circular RNA for protein expression 

      Wesselhoeft, R. Alexander(Robert Alexander) (Massachusetts Institute of Technology, 2019)
      Messenger RNA (mRNA) has broad potential for therapeutic and engineering applications. One fundamental limitation of mRNA is its relatively short half-life in biological systems, effected in part by rapid exonuclease-mediated ...
    • Cholesterol and egg activation 

      Wang, Li,Ph.D.Massachusetts Institute of Technology. (Massachusetts Institute of Technology, 2019)
      The high-density lipoprotein (HDL) receptor SR-BI controls the structure and fate of plasma HDL. The SR-BI knockout (KO) females are infertile, apparently due to their abnormal, cholesterol-enriched HDL particles. In this ...
    • Characterizing bacterial antibiotic resistance, prevalence, and persistence in the marine environment 

      May, Megan Katherine. (Massachusetts Institute of Technology, 2019)
      Antibiotics are naturally occurring chemicals in bacteria that were recently discovered and utilized by humans. Despite a relatively short time of use, anthropogenic use of antibiotics has increased natural levels of ...