Biological Engineering - Master's degree
Learning causal graphs under interventions and applications to single-cell biological data analysis (Massachusetts Institute of Technology, 2021)This thesis studies the problem of learning causal directed acyclic graphs (DAGs) in the setting where both observational and interventional data is available. This setting is common in biology, where gene regulatory ...
Computational analysis of intercellular communication in APC-driven colorectal cancers with varying KRas mutational status (Massachusetts Institute of Technology, 2020)Three common KRas mutants were compared with wild type KRas in a mouse model of APC-driven colorectal cancer to understand differences in cell-cell communication. Using single-cell RNA sequencing and a handful of novel ...