Browsing Biological Engineering Division by Title
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Browsing Biological Engineering Division by Title
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(Massachusetts Institute of Technology, 2004)This work describes the integration of novel microfabrication techniques for vascular tissue engineering applications in the context of a novel biodegradable elastomer. The field of tissue engineering and organ regeneration ...
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(Massachusetts Institute of Technology, 2004)Label-free detection is the detection of biomolecules and their interactions, without the use of a molecule external to the interaction, used as a reporter to indicate presence and/or location. The suspended microchannel ...
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(Massachusetts Institute of Technology, 2017)Living cells naturally use gene regulatory networks termed "genetic circuits" to exhibit complex behaviors such as signal processing, decision-making, and spatial organization. The ability to rationally engineer genetic ...
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(Massachusetts Institute of Technology, 2004)High affinity antibody binding interactions are important for both pharmaceutical and biotechnological uses. However, designing higher affinity interactions has remained difficult. Both high affinity interactions from ...
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(Massachusetts Institute of Technology, 2016)Cellular biophysical properties both reflect and influence cell state. These parameters represent the consequences of the interactions of multiple molecular events, and thus may reveal information otherwise obscured when ...
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(Massachusetts Institute of Technology, 2011)Angiogenesis is crucial during many physiological processes, and is influenced by various biochemical and biomechanical factors. Models have proven useful in understanding the mechanisms of angiogenesis and the characteristics ...
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(Massachusetts Institute of Technology, 2015)Biocatalysis has grown rapidly in recent decades as a solution to the evolving demands of industrial chemical processes. Mounting environmental pressures and shifting supply chains underscore the need for novel chemical ...
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(Massachusetts Institute of Technology, 2004)Recent epidemiological data has indicated that chronic exposure to metals such as arsenic and cadmium increases the risk of cancer and other diseases. These metals may have negative biological effects on cells by disrupting ...
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(Massachusetts Institute of Technology, 2007)Background: Investigators have focused on mechano-regulation of upstream signaling and responses at the level of gene transcription, protein translation and post-translational modifications. Intracellular pathways including ...
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(Massachusetts Institute of Technology, 2005)Chondroitin sulfate is a critical component of articular cartilage due to its contribution to the tissue's resistance to compressive deformation. Alterations in the biosynthesis of this molecule over time could impact the ...
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(Massachusetts Institute of Technology, 2008)Approximately one in five Americans is affected by arthritis, making it one of the most prevalent diseases and the leading cause of disability in the United States. Post-traumatic arthritis occurs after joint injury (e.g., ...
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(Massachusetts Institute of Technology, 2010)Metastasis is a multistep process during which tumor cells separate from a primary tumor, penetrate the bloodstream, evade host defenses, and colonize distant organs. This final and fatal step in tumor development is the ...
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(Massachusetts Institute of Technology, 2011)Traumatic brain injury (TBI) is a significant cause of death and morbidity in both the civilian and military populations. The major causes of TBI, such as motor vehicle accidents, falls, sports concussions, and ballistic ...
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(Massachusetts Institute of Technology, 2011)Cell size is often overlooked in the drive to define molecular mechanisms, but as a basic physical property it is an integrator of the cell's metabolic rate and indicator of cell fate. Development of the Suspended Microchannel ...
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(Massachusetts Institute of Technology, 2005)This study aims to investigate the relationships between growth parameters (agitation, glycerol concentration, salt concentration) and responses (biomass, growth rate, protein expression), by a 3-factor-3-level central ...
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(Massachusetts Institute of Technology, 2012)Preterm birth impacts 15 million babies every year, leading to morbidity, mortality, significant health care costs, and lifelong consequences. The causes of preterm birth are unknown, resulting in ineffective treatment, ...
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(Massachusetts Institute of Technology, 2011)Due to its common dysregulation in epithelial-based cancers and the extensive characterization of its role in tumor growth, epidermal growth factor receptor (EGFR) has long been an attractive target for monoclonal antibodies. ...
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 1996)
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(Massachusetts Institute of Technology, 2008)Despite increased awareness of the obesity epidemic and a higher incidence of the metabolic syndrome in humans, the incidence of obesity and its comorbidities-most notably, type II diabetes (T2D) and cardiovascular disease ...
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