Theses - Biological Engineering Division
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Theses - Biological Engineering Division
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(Massachusetts Institute of Technology, 2017)The ability to engineer complex genetic programs could have a huge impact on many industries, yielding organisms that can respond to their environment and perform functions relevant to manufacturing, agriculture, and ...
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(Massachusetts Institute of Technology, 2017)One of the major goals of systems biology is understanding how a cell changes from a healthy state to a diseased state. Entire fields of cell biology have been built around studying how changes in the type and abundance ...
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(Massachusetts Institute of Technology, 2017)Chemotherapy is widely used in the treatment of solid tumors, but its effects are often associated with cancer relapse, metastasis, and drug resistance. The biological mechanisms that drive the structural and functional ...
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(Massachusetts Institute of Technology, 2017)Checkpoint blockade with antibodies against CTLA-4 or PD-1 has demonstrated that an endogenous adaptive immune response can be stimulated to elicit durable tumor regressions in metastatic cancer, but these dramatic responses ...
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(Massachusetts Institute of Technology, 2017)Biological hydrogels exhibit complex properties that cannot be recapitulated by current synthetic materials. Examples include mucus, which acts as a barrier against toxins and pathogens while simultaneously hosting trillions ...
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