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Theses - Biological Engineering Division

Research and Teaching Output of the MIT Community

Theses - Biological Engineering Division

Recent Submissions

  • Streamlining and standardizing transcriptomic analysis in Amgen process development 
    Weinberg, Kerry Rachel (Massachusetts Institute of Technology, 2016)
    Building biological understanding of the Chinese Hamster Ovary (CHO) system used to manufacture therapeutic proteins is paramount to efficient CHO bioprocess optimization. This understanding can be built by analyzing and ...
  • Network analyses for functional genomic screens in cancer 
    Wilson, Jennifer L. (Jennifer Lynn) (Massachusetts Institute of Technology, 2016)
    Gene interference screens are a widely adopted and popular tool for uncovering gene function but imperfections in the technology limit the power of these investigations. There are many completed and on-going RNAi investigations ...
  • A 3D synthetic extracellular matrix that can be dissolved to interrogate the cellular local microenvironment on demand 
    Valdez Macias, Jorge L. (Jorge Luis) (Massachusetts Institute of Technology, 2016)
    In vitro multi-cellular 3D cultures can provide tremendous insight into pathologies arising from dysregulation of extracellular communication by recapitulating key features of the microenvironment, such as ECM-cytokine ...
  • Improving methods for cytokine immunotherapy of cancer 
    Tzeng, Alice (Massachusetts Institute of Technology, 2016)
    Cytokine therapy can activate potent antitumor responses, yet collateral toxicity often limits dosages. Although immunocytokines have been designed with the intent to localize cytokine activity, systemic dose-limiting side ...
  • Molecular imaging with engineered physiology 
    Slusarczyk, Adrian L. (Adrian Lukas) (Massachusetts Institute of Technology, 2016)
    Using molecular imaging in vivo, biomolecular and cellular phenomena can be investigated within their relevant physiological context, addressing a central challenge for 21st century biomedicine and basic research. To advance ...
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