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Theses - Biological Engineering Division

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Theses - Biological Engineering Division

Recent Submissions

  • Expansion microscopy : scalable and multiplexed nanoscale imaging 
    Chen, Fei, Ph. D. Massachusetts Institute of Technology. Department of Biological Engineering (Massachusetts Institute of Technology, 2017)
    Microscopy has facilitated the discovery of many biological insights by optically magnifying small structures in cells and tissues. However, the resolution of optical microscopy is limited by the diffraction of light to ...
  • Systems biology of diet-induced hepatic insulin resistance 
    Soltis, Anthony Robert (Massachusetts Institute of Technology, 2017)
    Human obesity is a world-wide health crisis that promotes insulin resistance and type 2 diabetes. Obesity increases intracellular free fatty acid concentrations in peripheral tissues, particularly the liver, which disrupts ...
  • Decoding structure-function relationships of glycans 
    Stebbins, Nathan Wilson (Massachusetts Institute of Technology, 2017)
    Glycans are an important class of biological molecules that regulate a variety of physiological processes such as signal transduction, tissue development and microbial pathogenesis. However, due to the structural complexity ...
  • Molecular pathway analysis and therapeutics development in post-traumatic osteoarthritis 
    Wang, Yang, Ph. D. Massachusetts Institute of Technology (Massachusetts Institute of Technology, 2017)
    Post traumatic osteoarthritis (PTOA) refers to the progressive degradation of cartilage often triggered by a traumatic joint injury, such as a tear of the meniscus or anterior cruciate ligament (ACL). Such impact injuries ...
  • Computational engineering of small molecules to treat infectious diseases 
    Srinivas, Raja R (Massachusetts Institute of Technology, 2017)
    Rational drug design of small molecules has led to the development of robust therapeutics that are currently used in the clinic. However, key challenges remain in designing drugs against infectious disease targets that are ...
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