Now showing items 1-3 of 1026

    • Dynamic regulation and functions of locus-specific DNA methylation 

      Song, Yuelin,Ph. D.Massachusetts Institute of Technology. (Massachusetts Institute of Technology, 2020)
      The role and regulation of DNA methylation at various genetic elements have gathered tremendous interest over decades. The methylomes of many cell types have been described, revealing a dynamic and tissue-specific pattern ...
    • Engineering probiotic microbes for in vivo applications 

      Müller, Isaak Elis. (Massachusetts Institute of Technology, 2020)
      Our overall goal is to engineer probiotic microbes as localized diagnostic and therapeutic tools for diseases in the gastrointestinal tract, like inflammatory bowel disease. Current treatments often rely on systemic ...
    • Choices in regeneration: position and fate 

      Raz, Amelie A. (Massachusetts Institute of Technology, 2020)
      Positional information is required for animal regeneration, yet how it is harbored in adult tissues is poorly understood. In planarians, positional control genes (PCGs) control regeneration outcomes and are regionally ...