Now showing items 1-3 of 908

    • Genetic technologies to engineer and understand the microbiome 

      Mimee, Mark(Mark K.) (Massachusetts Institute of Technology, 2018)
      The microbes that inhabit the human body are integral to human health and disease: from inflammatory bowel disease to allergy, metabolic syndrome to autism. Due to its high connectivity with human physiology, manipulation ...
    • Synthetic circular RNA for protein expression 

      Wesselhoeft, R. Alexander(Robert Alexander) (Massachusetts Institute of Technology, 2019)
      Messenger RNA (mRNA) has broad potential for therapeutic and engineering applications. One fundamental limitation of mRNA is its relatively short half-life in biological systems, effected in part by rapid exonuclease-mediated ...
    • Cholesterol and egg activation 

      Wang, Li,Ph.D.Massachusetts Institute of Technology. (Massachusetts Institute of Technology, 2019)
      The high-density lipoprotein (HDL) receptor SR-BI controls the structure and fate of plasma HDL. The SR-BI knockout (KO) females are infertile, apparently due to their abnormal, cholesterol-enriched HDL particles. In this ...