Recent Submissions

  • Development of a reactive peptide sequence for site-selective bioconjugation 

    Tuang, Suan Lian. (Massachusetts Institute of Technology, 2020)
    Achieving catalyst-free, site-selective modification of proteins in water is a significant challenge in chemical biology. Issues of residue specificity, site-selectivity, reagent stability, and reaction rate are pervasive ...
  • Palladium catalyzed cross-coupling of esters and amides 

    Shinabery, Ryan Spence. (Massachusetts Institute of Technology, 2019)
    Over the last 40 years, great strides have been made in the use of palladium as both a catalyst and a reagent for a multitude of chemical transformations that have had tremendous impacts all walks of life from material ...
  • Palladium- and nickel-catalyzed C-N cross-coupling reactions featuring soluble organic bases 

    Dennis, Joseph Michael,Jr. (Massachusetts Institute of Technology, 2020)
    Chapter 1: Breaking the Base Barrier: An Electron-Deficient Palladium Catalyst Enables the Use of a Common Soluble Base in C-N Coupling Due to the low intrinsic acidity of amines, palladium-catalyzed C-N cross-coupling ...

View more