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dc.contributor.authorLaulicht, Bryan E.
dc.contributor.authorLanger, Robert
dc.contributor.authorKarp, Jeffrey Michael
dc.date.accessioned2013-05-13T20:20:16Z
dc.date.available2013-05-13T20:20:16Z
dc.date.issued2012-10
dc.identifier.issn0027-8424
dc.identifier.issn1091-6490
dc.identifier.urihttp://hdl.handle.net/1721.1/78867
dc.description.abstractMedical tape that provides secure fixation of life-sustaining and -monitoring devices with quick, easy, damage-free removal represents a longstanding unmet medical need in neonatal care. During removal of current medical tapes, crack propagation occurs at the adhesive–skin interface, which is also the interface responsible for device fixation. By designing quick-release medical tape to undergo crack propagation between the backing and adhesive layers, we decouple removal and device fixation, enabling dual functionality. We created an ordered adhesive/antiadhesive composite intermediary layer between the medical tape backing and adhesive for which we achieve tunable peel removal force, while maintaining high shear adhesion to secure medical devices. We elucidate the relationship between the spatial ordering of adhesive and antiadhesive regions to create a fully tunable system that achieves strong device fixation and quick, easy, damage-free device removal. We also described ways of neutralizing the residual adhesive on the skin and have observed that thick continuous films of adhesive are easier to remove than the thin islands associated with residual adhesive left by current medical tapes.en_US
dc.description.sponsorshipPhilips Children’s Medical Ventures (Institute for Pediatric Innovation)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant DE013023)en_US
dc.description.sponsorshipNational Institutes of Health (U.S.) (Grant GM086433)en_US
dc.language.isoen_US
dc.publisherNational Academy of Sciences (U.S.)en_US
dc.relation.isversionofhttp://dx.doi.org/10.1073/pnas.1216071109en_US
dc.rightsArticle is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use.en_US
dc.sourcePNASen_US
dc.titleQuick-release medical tapeen_US
dc.typeArticleen_US
dc.identifier.citationLaulicht, B., R. Langer, and J. M. Karp 2012Quick-release Medical Tape. Proceedings of the National Academy of Sciences 109(46): 18803–18808.en_US
dc.contributor.departmentHarvard University--MIT Division of Health Sciences and Technologyen_US
dc.contributor.departmentMassachusetts Institute of Technology. Department of Chemical Engineeringen_US
dc.contributor.mitauthorLaulicht, Bryan E.
dc.contributor.mitauthorLanger, Robert
dc.contributor.mitauthorKarp, Jeffrey Michael
dc.relation.journalProceedings of the National Academy of Sciences of the United States of Americaen_US
dc.eprint.versionFinal published versionen_US
dc.type.urihttp://purl.org/eprint/type/JournalArticleen_US
eprint.statushttp://purl.org/eprint/status/PeerRevieweden_US
dspace.orderedauthorsLaulicht, B.; Langer, R.; Karp, J. M.en
dc.identifier.orcidhttps://orcid.org/0000-0003-4255-0492
mit.licensePUBLISHER_POLICYen_US
mit.metadata.statusComplete


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