Browsing Harvard-MIT Program of Health Sciences and Technology by Title
Now showing items 253-272 of 626
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A hair bundle proteomics approach to discovering actin regulatory proteins in inner ear stereocilia
(Massachusetts Institute of Technology, 2009)Because there is little knowledge in the areas of stereocilia development, maintenance, and function in the hearing system, I decided to pursue a proteomics-based approach to discover proteins that play a role in stereocilia ... -
Health care self-selection in a multiple option corporate benefit program
(Massachusetts Institute of Technology, 1990) -
Health information on the Internet : strategies for assessing consumer needs and improving consumer information retrieval
(Massachusetts Institute of Technology, 2004)Patients and their family members are increasingly turning to the Internet for health information. However, the search strategies consumers are using to obtain information are often unsuccessful. Since some patients are ... -
Heart transplantation--is there a relation between experience and outcome?
(Massachusetts Institute of Technology, 1991) -
Heparan sulfate glycosaminoglycan regulation of vasculogenesis
(Massachusetts Institute of Technology, 2011)Neovascularization is an essential process to repair ischemic tissues following myocardial infarction, stroke, diabetic complications, or transplant procedures. Blood vessels are generated by distinct vasculogenic and ... -
Hidden Markov Model inference copy number change in array-CGH data
(Massachusetts Institute of Technology, 2005)Cancer development and progression typically features genomic instability frequently resulting in genomic changes involving DNA copy number gains or losses. Identifying the genomic location of these regional alterations ... -
High resolution imaging of neoplasma using optical coherence tomography
(Massachusetts Institute of Technology, 2000)Diagnostic imaging technologies for the detection of cancer include CT, MRI, ultrasonography, and endoscopy. However, many early neoplastic changes remain beyond their detection limits. A modality capable of imaging at or ... -
High-throughput approaches to sourcing of human hepatocytes for cell-based therapies
(Massachusetts Institute of Technology, 2014)Chronic liver disease affects more than 500 million people worldwide. The only therapy shown to directly prevent mortality is organ transplantation. However, there is growing discrepancy between supply and demand of ... -
High-throughput experimental and computational tools for exploring immunity and the microbiome
(Massachusetts Institute of Technology, 2012)Humans live in association with trillions of microbes and yet we know remarkably little about their symbiotic relationship. The role these microorganisms have in humans has been characterized only in the case of few bacteria ... -
High-throughput methods for characterizing the immune repertoire
(Massachusetts Institute of Technology, 2013)The adaptive immune system is one of the primary mediators in almost every major human disease, including infections, cancer, autoimmunity, and inflammation-based disorders. It fundamentally functions as a molecular ... -
High-throughput microfluidic living cell arrays for spatiotemporal gene expression profiling
(Massachusetts Institute of Technology, 2008)The cellular microenvironment is remarkably complex. In the small space near each cell, growth factors are liberated from extracellular matrix, cytokines are secreted from neighboring cells, and hormones arrive from distant ... -
Hip fracture and fall impact biomechanics
(Massachusetts Institute of Technology, 1994) -
Hip fracture risk predictions by x-ray computed tomography
(Massachusetts Institute of Technology, 1988) -
The human molecular clock and mutation process : a characterization using microsatellite DNA
(Massachusetts Institute of Technology, 2012)In the past decade, thousands of human genomes have been catalogued, either by whole-genome sequencing or by targeted genotyping. The variability between human genomes encodes invaluable information about human traits and ... -
Identification of a gap junction communication pathway critical in innate immunity
(Massachusetts Institute of Technology, 2010)The innate immune system is the first line of host defense, and its ability to propagate antimicrobial and inflammatory signals from the cellular microenvironment to the tissue at-large is critical for survival. In a ... -
Identification of clinical characteristics of large patient cohorts through analysis of free text physician notes
(Massachusetts Institute of Technology, 2005)Background A number of important applications in medicine and biomedical research, including quality of care surveillance and identification of prospective study subjects, require identification of large cohorts of patients ... -
Identifying genes that are required for the maintenance of pancreatic ductal adenocarcinoma
(Massachusetts Institute of Technology, 2012)We searched for genes that are potentially important for the maintenance of Pancreatic Ductal Adenocarcinoma (PDAC). PDAC is the 4th leading cause for cancer-related deaths and exhibits a 5-year survival rate of less than ... -
Image guidance in cardiac electrophysiology
(Massachusetts Institute of Technology, 2006)Cardiac arrhythmias are characterized by a disruption or abnormal conduction of electrical signals within the heart. Treatment of arrhythmias has dramatically evolved over the past half-century, and today, minimally-invasive ... -
The impact of angel investors on founders of new ventures in the medical technology industry
(Massachusetts Institute of Technology, 2011)Founders of new ventures in the medical technology (Medtech) industry require capital to establish, sustain, and grow their companies. Most founders must seek some form of external capital to meet these demands; in Medtech, ... -
Impact of human vocal fold vibratory asymmetries on acoustic characteristics of sustained vowel phonation
(Massachusetts Institute of Technology, 2010)Clinical voice specialists make critical diagnostic, medical, therapeutic, and surgical decisions by coupling visual observations of vocal fold tissue motion with auditory-perceptual assessments of voice quality. The details ...
