| dc.contributor.author | Tsvelikhovsky, Dmitry | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2013-11-04T15:10:57Z | |
| dc.date.available | 2013-11-04T15:10:57Z | |
| dc.date.issued | 2011-08 | |
| dc.date.submitted | 2011-07 | |
| dc.identifier.issn | 0002-7863 | |
| dc.identifier.issn | 1520-5126 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/81965 | |
| dc.description.abstract | A general and highly efficient protocol for the synthesis of dibenzodiazepines and their structural analogues is reported. In the presence of catalytic quantities of palladium, readily accessible precursors are cross-coupled with ammonia and then spontaneously undergo an intramolecular condensation to form the corresponding dibenzodiazepines in one step. This new strategy is applicable to the construction of a wide variety of dibenzooxazepines and other structurally related heterocycles. | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Grant GM-58160) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ja206229y | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | Concise Palladium-Catalyzed Synthesis of Dibenzodiazepines and Structural Analogs | en_US |
| dc.title.alternative | Concise Palladium-Catalyzed Synthesis of Dibenzodiazepines and Structural Analogues | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Tsvelikhovsky, Dmitry, and Stephen L. Buchwald. “Concise Palladium-Catalyzed Synthesis of Dibenzodiazepines and Structural Analogues.” Journal of the American Chemical Society 133, no. 36 (September 14, 2011): 14228-14231. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Tsvelikhovsky, Dmitry | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Journal of the American Chemical Society | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Tsvelikhovsky, Dmitry; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
