| dc.contributor.author | Cho, Eun Jin | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2013-11-04T15:27:47Z | |
| dc.date.available | 2013-11-04T15:27:47Z | |
| dc.date.issued | 2011-11 | |
| dc.date.submitted | 2011-10 | |
| dc.identifier.issn | 1523-7060 | |
| dc.identifier.issn | 1523-7052 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/81967 | |
| dc.description.abstract | A method for the palladium-catalyzed trifluoromethylation of cyclohexenyl sulfonates has been developed. Various cyclohexenyl triflates and nonaflates underwent trifluoromethylation under mild reaction conditions using a catalyst system composed of Pd(dba)[subscript 2] or [(allyl)PdCl][subscript 2] and the monodentate biaryl phosphine ligand [superscript t]BuXPhos. The trifluoromethyl anion (CF[– over 3]) or its equivalent for the process was generated in situ from TMSCF[subscript 3] in combination with KF or TESCF[subscript 3] in combination with RbF. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Grant GM46059) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ol202885w | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | The Palladium-Catalyzed Trifluoromethylation of Vinyl Sulfonates | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Cho, Eun Jin, and Stephen L. Buchwald. “The Palladium-Catalyzed Trifluoromethylation of Vinyl Sulfonates.” Organic Letters 13, no. 24 (December 16, 2011): 6552-6555. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Cho, Eun Jin | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Cho, Eun Jin; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
