The Genotype-Tissue Expression (GTEx) project
| dc.contributor.author | Kellis, Manolis | |
| dc.date.accessioned | 2014-05-22T15:32:07Z | |
| dc.date.available | 2014-05-22T15:32:07Z | |
| dc.date.issued | 2013-05 | |
| dc.identifier.issn | 1061-4036 | |
| dc.identifier.issn | 1546-1718 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/87085 | |
| dc.description.abstract | Genome-wide association studies have identified thousands of loci for common diseases, but, for the majority of these, the mechanisms underlying disease susceptibility remain unknown. Most associated variants are not correlated with protein-coding changes, suggesting that polymorphisms in regulatory regions probably contribute to many disease phenotypes. Here we describe the Genotype-Tissue Expression (GTEx) project, which will establish a resource database and associated tissue bank for the scientific community to study the relationship between genetic variation and gene expression in human tissues. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (US NIH to the Broad Institute of Harvard and MIT, R01 DA006227-17) | en_US |
| dc.description.sponsorship | National Institute of Drug Abuse | en_US |
| dc.description.sponsorship | National Institute of Mental Health (U.S.) | en_US |
| dc.description.sponsorship | National Institute of Neurological Disorders and Stroke (U.S.) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Nature Publishing Group | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1038/ng.2653 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | The Genotype-Tissue Expression (GTEx) project | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Lonsdale, John, Jeffrey Thomas, Mike Salvatore, Rebecca Phillips, Edmund Lo, Saboor Shad, Richard Hasz, et al. “The Genotype-Tissue Expression (GTEx) Project.” Nature Genetics 45, no. 6 (May 29, 2013): 580–585. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science | en_US |
| dc.contributor.mitauthor | Kellis, Manolis | en_US |
| dc.relation.journal | Nature Genetics | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Lonsdale, John; Thomas, Jeffrey; Salvatore, Mike; Phillips, Rebecca; Lo, Edmund; Shad, Saboor; Hasz, Richard; Walters, Gary; Garcia, Fernando; Young, Nancy; Foster, Barbara; Moser, Mike; Karasik, Ellen; Gillard, Bryan; Ramsey, Kimberley; Sullivan, Susan; Bridge, Jason; Magazine, Harold; Syron, John; Fleming, Johnelle; Siminoff, Laura; Traino, Heather; Mosavel, Maghboeba; Barker, Laura; Jewell, Scott; Rohrer, Dan; Maxim, Dan; Filkins, Dana; Harbach, Philip; Cortadillo, Eddie; Berghuis, Bree; Turner, Lisa; Hudson, Eric; Feenstra, Kristin; Sobin, Leslie; Robb, James; Branton, Phillip; Korzeniewski, Greg; Shive, Charles; Tabor, David; Qi, Liqun; Groch, Kevin; Nampally, Sreenath; Buia, Steve; Zimmerman, Angela; Smith, Anna; Burges, Robin; Robinson, Karna; Valentino, Kim; Bradbury, Deborah; Cosentino, Mark; Diaz-Mayoral, Norma; Kennedy, Mary; Engel, Theresa; Williams, Penelope; Erickson, Kenyon; Ardlie, Kristin; Winckler, Wendy; Getz, Gad; DeLuca, David; MacArthur, Daniel; Kellis, Manolis; Thomson, Alexander; Young, Taylor; Gelfand, Ellen; Donovan, Molly; Meng, Yan; Grant, George; Mash, Deborah; Marcus, Yvonne; Basile, Margaret; Liu, Jun; Zhu, Jun; Tu, Zhidong; Cox, Nancy J; Nicolae, Dan L; Gamazon, Eric R; Im, Hae Kyung; Konkashbaev, Anuar; Pritchard, Jonathan; Stevens, Matthew; Flutre, Timothèe; Wen, Xiaoquan; Dermitzakis, Emmanouil T; Lappalainen, Tuuli; Guigo, Roderic; Monlong, Jean; Sammeth, Michael; Koller, Daphne; Battle, Alexis; Mostafavi, Sara; McCarthy, Mark; Rivas, Manual; Maller, Julian; Rusyn, Ivan; Nobel, Andrew; Wright, Fred; Shabalin, Andrey; Feolo, Mike; Sharopova, Nataliya; Sturcke, Anne; Paschal, Justin; Anderson, James M; Wilder, Elizabeth L; Derr, Leslie K; Green, Eric D; Struewing, Jeffery P; Temple, Gary; Volpi, Simona; Boyer, Joy T; Thomson, Elizabeth J; Guyer, Mark S; Ng, Cathy; Abdallah, Assya; Colantuoni, Deborah; Insel, Thomas R; Koester, Susan E; Little, A Roger; Bender, Patrick K; Lehner, Thomas; Yao, Yin; Compton, Carolyn C; Vaught, Jimmie B; Sawyer, Sherilyn; Lockhart, Nicole C; Demchok, Joanne; Moore, Helen F | en_US |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete |
