Development of a chronically implanted microelectrode array for intraneural electrical stimulation for prosthetic sensory feedback

Author(s)
DiLorenzo, Daniel John
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Harvard University--MIT Division of Health Sciences and Technology.
Advisor
David J. Edell.
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Abstract
The functionality of prosthetic limbs is restricted by the limited availability of sensory feedback. This research aims to develop a technology to allow the presentation of sensory information directly to the sensory afferent neurons of the transected peripheral nerve in the stump of the amputee. lntraneural implants of several designs were developed and implanted in rabbit animal models and monitored for chronic functionality evaluated using both neurophysiological and behavioral tests. Animal studies have demonstrated single channel implant functionality of up to 129 days. The relative merit of the designs is assessed, and future directions for implant design and behavioral testing are suggested.
Description
Thesis (S.M.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology, 1999.
 
Includes bibliographical references (leaves 42-44).
 
Date issued
1999
URI
http://hdl.handle.net/1721.1/9329
Department
Harvard University--MIT Division of Health Sciences and Technology
Publisher
Massachusetts Institute of Technology
Keywords
Harvard University--MIT Division of Health Sciences and Technology.
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