Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst

Author(s)
Cheung, Chi Wai; Buchwald, Stephen Leffler
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Abstract
A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.
Date issued
2013-07
URI
http://hdl.handle.net/1721.1/93912
Department
Massachusetts Institute of Technology. Department of Chemistry
Journal
Organic Letters
Publisher
American Chemical Society (ACS)
Citation
Cheung, Chi Wai, and Stephen L. Buchwald. “Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst.” Org. Lett. 15, no. 15 (August 2, 2013): 3998–4001.
Version: Author's final manuscript
ISSN
1523-7060
1523-7052
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