Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst
Author(s)Cheung, Chi Wai; Buchwald, Stephen Leffler
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A general method for the Pd-catalyzed coupling of methanol with (hetero)aryl halides is described. The reactions proceed under mild conditions with a wide range of aryl and heteroaryl halides to give methyl aryl ethers in high yield.
DepartmentMassachusetts Institute of Technology. Department of Chemistry
American Chemical Society (ACS)
Cheung, Chi Wai, and Stephen L. Buchwald. “Mild and General Palladium-Catalyzed Synthesis of Methyl Aryl Ethers Enabled by the Use of a Palladacycle Precatalyst.” Org. Lett. 15, no. 15 (August 2, 2013): 3998–4001.
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