| dc.contributor.author | Chen, Mao | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.date.accessioned | 2015-02-06T20:03:01Z | |
| dc.date.available | 2015-02-06T20:03:01Z | |
| dc.date.issued | 2013-09 | |
| dc.date.submitted | 2013-07 | |
| dc.identifier.issn | 14337851 | |
| dc.identifier.issn | 1521-3773 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/93915 | |
| dc.description.abstract | The trifluoromethylation of aryl/heteroaryl iodides has been demonstrated using a flow system, thus enabling a rapid rate of reaction. A broad spectrum of trifluoromethylated compounds was prepared in good to excellent yields using CF[subscript 3]CO[subscript 2]K as the trifluoromethyl source. The process has the advantage of short reaction times and uses convenient [CF[subscript 3]] sources. | en_US |
| dc.description.sponsorship | Novartis (Firm) | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (GM46059) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Wiley Blackwell | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1002/anie.201306094 | en_US |
| dc.rights | Creative Commons Attribution-Noncommercial-Share Alike | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | Rapid and Efficient Trifluoromethylation of Aromatic and Heteroaromatic Compounds Using Potassium Trifluoroacetate Enabled by a Flow System | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Chen, Mao, and Stephen L. Buchwald. “Rapid and Efficient Trifluoromethylation of Aromatic and Heteroaromatic Compounds Using Potassium Trifluoroacetate Enabled by a Flow System.” Angewandte Chemie International Edition 52, no. 44 (September 5, 2013): 11628–11631. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Chen, Mao | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.relation.journal | Angewandte Chemie International Edition | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Chen, Mao; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| dc.identifier.orcid | https://orcid.org/0000-0002-7374-8680 | |
| mit.license | OPEN_ACCESS_POLICY | en_US |
| mit.metadata.status | Complete | |
