| dc.contributor.author | Lee, Hong Geun | |
| dc.contributor.author | Buchwald, Stephen Leffler | |
| dc.contributor.author | Milner, Phillip John | |
| dc.date.accessioned | 2015-02-12T16:23:38Z | |
| dc.date.available | 2015-02-12T16:23:38Z | |
| dc.date.issued | 2013-11 | |
| dc.date.submitted | 2013-10 | |
| dc.identifier.issn | 1523-7060 | |
| dc.identifier.issn | 1523-7052 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/94490 | |
| dc.description.abstract | The stable Pd(0) species [(1,5-cyclooctadiene)(L·Pd)[subscript 2]] (L = AdBrettPhos) has been prepared and successfully evaluated as a precatalyst for the fluorination of aryl triflates derived from biologically active and heteroaryl phenols, challenging substrates for our previously reported catalyst system. Additionally, this precatalyst activates at room temperature under neutral conditions, generates 1,5-cyclooctadiene as the only byproduct, and leads to overall cleaner reaction profiles. | en_US |
| dc.description.sponsorship | National Institutes of Health (U.S.) (Award GM46059) | en_US |
| dc.description.sponsorship | Amgen Inc. | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (2010094243) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Grant CHE 980861) | en_US |
| dc.description.sponsorship | National Science Foundation (U.S.) (Grant DBI 9729592) | en_US |
| dc.language.iso | en_US | |
| dc.publisher | American Chemical Society (ACS) | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1021/ol402859k | en_US |
| dc.rights | Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. | en_US |
| dc.source | PMC | en_US |
| dc.title | An Improved Catalyst System for the Pd-Catalyzed Fluorination of (Hetero)Aryl Triflates | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Lee, Hong Geun, Phillip J. Milner, and Stephen L. Buchwald. “An Improved Catalyst System for the Pd-Catalyzed Fluorination of (Hetero)Aryl Triflates.” Org. Lett. 15, no. 21 (November 2013): 5602–5605. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemistry | en_US |
| dc.contributor.mitauthor | Buchwald, Stephen Leffler | en_US |
| dc.contributor.mitauthor | Milner, Phillip John | en_US |
| dc.contributor.mitauthor | Lee, Hong Geun | en_US |
| dc.relation.journal | Organic Letters | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Lee, Hong Geun; Milner, Phillip J.; Buchwald, Stephen L. | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0003-3875-4775 | |
| dc.identifier.orcid | https://orcid.org/0000-0001-8075-1100 | |
| mit.license | PUBLISHER_POLICY | en_US |
| mit.metadata.status | Complete | |
