MIT Libraries homeMIT Libraries logoDSpace@MIT

MIT
View Item 
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • View Item
  • DSpace@MIT Home
  • MIT Open Access Articles
  • MIT Open Access Articles
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Dynamic nuclear polarization at 9 T using a novel 250 GHz gyrotron microwave source

Author(s)
Bajaj, Vikram S.; Farrar, C. T.; Hornstein, Melissa K.; Mastovsky, Ivan; Vieregg, Jeffrey; Bryant, Jeffrey A.; Elena, B.; Kreischer, K. E.; Griffin, Robert Guy; Temkin, Richard J; ... Show more Show less
Thumbnail
DownloadGriffin_Dynamic nuclear polarization.pdf (778.7Kb)
PUBLISHER_CC

Publisher with Creative Commons License

Creative Commons Attribution

Terms of use
Creative Commons Attribution-Noncommercial-NoDerivatives http://creativecommons.org/licenses/by-nc-nd/4.0/
Metadata
Show full item record
Abstract
In this communication, we report enhancements of nuclear spin polarization by dynamic nuclear polarization (DNP) in static and spinning solids at a magnetic field strength of 9 T (250 GHz for g = 2 electrons, 380 MHz for [superscript 1]H). In these experiments, [superscript 1]H enhancements of up to 170 ± 50 have been observed in 1-[superscript 13]C-glycine dispersed in a 60:40 glycerol/water matrix at temperatures of 20 K; in addition, we have observed significant enhancements in [superscript 15]N spectra of unoriented pf1-bacteriophage. Finally, enhancements of ~17 have been obtained in two-dimensional [superscript 13]C–[superscript 13]C chemical shift correlation spectra of the amino acid U–[superscript 13]C, [superscript 15]N-proline during magic angle spinning (MAS), demonstrating the stability of the DNP experiment for sustained acquisition and for quantitative experiments incorporating dipolar recoupling. In all cases, we have exploited the thermal mixing DNP mechanism with the nitroxide radical 4-amino-TEMPO as the paramagnetic dopant. These are the highest frequency DNP experiments performed to date and indicate that significant signal enhancements can be realized using the thermal mixing mechanism even at elevated magnetic fields. In large measure, this is due to the high microwave power output of the 250 GHz gyrotron oscillator used in these experiments.
Date issued
2011-12
URI
http://hdl.handle.net/1721.1/99503
Department
Massachusetts Institute of Technology. Department of Chemistry; Massachusetts Institute of Technology. Department of Physics; Massachusetts Institute of Technology. Plasma Science and Fusion Center; Francis Bitter Magnet Laboratory (Massachusetts Institute of Technology)
Journal
Journal of Magnetic Resonance
Publisher
Elsevier
Citation
Bajaj, V.S., C.T. Farrar, M.K. Hornstein, I. Mastovsky, J. Vieregg, J. Bryant, B. Eléna, K.E. Kreischer, R.J. Temkin, and R.G. Griffin. “Dynamic Nuclear Polarization at 9T Using a Novel 250GHz Gyrotron Microwave Source.” Journal of Magnetic Resonance 213, no. 2 (December 2011): 404–409.
Version: Author's final manuscript
ISSN
10907807
1096-0856

Collections
  • MIT Open Access Articles

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

Login

Statistics

OA StatisticsStatistics by CountryStatistics by Department
MIT Libraries homeMIT Libraries logo

Find us on

Twitter Facebook Instagram YouTube RSS

MIT Libraries navigation

SearchHours & locationsBorrow & requestResearch supportAbout us
PrivacyPermissionsAccessibility
MIT
Massachusetts Institute of Technology
Content created by the MIT Libraries, CC BY-NC unless otherwise noted. Notify us about copyright concerns.