<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-19T02:40:36Z</responseDate><request verb="GetRecord" identifier="oai:dspace.mit.edu:1721.1/100890" metadataPrefix="dim">https://dspace.mit.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:dspace.mit.edu:1721.1/100890</identifier><datestamp>2022-01-18T16:49:56Z</datestamp><setSpec>com_1721.1_7582</setSpec><setSpec>com_1721.1_7581</setSpec><setSpec>col_1721.1_131023</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="advisor" lang="en_US">Joseph Jacobson.</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">Fracchia, Charles (Charles Victor)</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="other" lang="en_US">Massachusetts Institute of Technology. Department of Architecture. Program in Media Arts and Sciences.</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="department">Program in Media Arts and Sciences (Massachusetts Institute of Technology)</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2016-01-15T21:11:24Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="available">2016-01-15T21:11:24Z</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="copyright" lang="en_US">2014</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="issued" lang="en_US">2014</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="uri">http://hdl.handle.net/1721.1/100890</dim:field>
   <dim:field mdschema="dc" element="identifier" qualifier="oclc" lang="en_US">933611231</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Thesis: S.M., Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2014.</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Cataloged from PDF version of thesis.</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Includes bibliographical references (pages 95-100).</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">Current biological research workflows make use of disparate, poorly integrated systems that cause large mental burden on the scientist leading to mistakes on often long, complex and costly experimental procedures. The lack of open tools to assist in the collection of distributed experimental conditions and data is largely responsible making protocols difficult to debug and laboratory practice hard to learn. In this thesis, we describe an open Protocol Descriptor Language (PDL) and system to enable a context-rich, quantitative approach to biological research. We detail the development of a closed-loop pipetting technology and a wireless, sample temperature sensor that integrate with our Protocol Description platform enabling novel, real-time experimental feedback to the researcher thereby reducing mistakes and increasing overall scientific reproducibility.</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="statementofresponsibility" lang="en_US">by Charles Fracchia.</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="degree" lang="en_US">S.M.</dim:field>
   <dim:field mdschema="dc" element="format" qualifier="extent" lang="en_US">100 pages</dim:field>
   <dim:field mdschema="dc" element="language" qualifier="iso" lang="en_US">eng</dim:field>
   <dim:field mdschema="dc" element="publisher" lang="en_US">Massachusetts Institute of Technology</dim:field>
   <dim:field mdschema="dc" element="rights" lang="en_US">M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.</dim:field>
   <dim:field mdschema="dc" element="rights" qualifier="uri" lang="en_US">http://dspace.mit.edu/handle/1721.1/7582</dim:field>
   <dim:field mdschema="dc" element="subject" lang="en_US">Architecture. Program in Media Arts and Sciences.</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">Language &amp; tools for context-aware biology</dim:field>
   <dim:field mdschema="dc" element="title" qualifier="alternative" lang="en_US">Language and tools for context-aware biology</dim:field>
   <dim:field mdschema="dc" element="type" lang="en_US">Thesis</dim:field>
   <dim:field mdschema="dc" element="format" qualifier="mimetype">application/pdf</dim:field>
   <dim:field mdschema="dspace" element="authorsordered">false</dim:field>
   <dim:field mdschema="dspace" element="entity" qualifier="type">Publication</dim:field>
   <dim:field mdschema="others" element="access-status">unknown</dim:field>
   <dim:field mdschema="others" element="access-status">unknown</dim:field>
   <dim:field mdschema="cerif" element="openaire" authority="" confidence="-1">&lt;Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="ba424991-0ef0-4125-81b3-3c63af97db4c">
	&lt;Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843&lt;/Type>
	&lt;Language>eng&lt;/Language>
   	&lt;Title>Language &amp;amp; tools for context-aware biology&lt;/Title>
   	&lt;Subtitle>Language and tools for context-aware biology&lt;/Subtitle>
   	&lt;PublishedIn>
    	&lt;Publication>
      	&lt;/Publication>
   	&lt;/PublishedIn>
   	&lt;PublicationDate>2014&lt;/PublicationDate>
   	&lt;Authors>
      	&lt;Author>
        	&lt;DisplayName>Fracchia, Charles (Charles Victor)&lt;/DisplayName>
         	&lt;Affiliation>
         		&lt;OrgUnit>
         		&lt;/OrgUnit>
         	&lt;/Affiliation>
      	&lt;/Author>
	&lt;/Authors>
   	&lt;Editors>
	&lt;/Editors>
    &lt;Publishers>
        &lt;Publisher>
            &lt;DisplayName>Massachusetts Institute of Technology&lt;/DisplayName>
            &lt;OrgUnit />
        &lt;/Publisher>
    &lt;/Publishers>
    &lt;License>http://dspace.mit.edu/handle/1721.1/7582&lt;/License>
    &lt;Keyword>Architecture. Program in Media Arts and Sciences.&lt;/Keyword>
   	&lt;Abstract>Current biological research workflows make use of disparate, poorly integrated systems that cause large mental burden on the scientist leading to mistakes on often long, complex and costly experimental procedures. The lack of open tools to assist in the collection of distributed experimental conditions and data is largely responsible making protocols difficult to debug and laboratory practice hard to learn. In this thesis, we describe an open Protocol Descriptor Language (PDL) and system to enable a context-rich, quantitative approach to biological research. We detail the development of a closed-loop pipetting technology and a wireless, sample temperature sensor that integrate with our Protocol Description platform enabling novel, real-time experimental feedback to the researcher thereby reducing mistakes and increasing overall scientific reproducibility.&lt;/Abstract>
	&lt;Access xmlns="http://purl.org/coar/access_right" 
    >
    &lt;/Access>
&lt;/Publication>
</dim:field>
</dim:dim>
</metadata></record></GetRecord></OAI-PMH>