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Linn W. Hobbs. Reese, Willie Mae Massachusetts Institute of Technology. Department of Materials Science and Engineering. Massachusetts Institute of Technology. Department of Materials Science and Engineering 2017-12-05T19:15:23Z 2017-12-05T19:15:23Z 2010 2010 http://hdl.handle.net/1721.1/112495 1011512390 Thesis: S.B., Massachusetts Institute of Technology, Department of Materials Science and Engineering, June 2010. "May 2009." Page 47 blank. Cataloged from PDF version of thesis. Includes bibliographical references (pages 28-29). The present study investigates the naturally occurring interface between bone and tendon using scanning electron microscopy. The micrographs revealed a cartilaginous layer, 100 to 400 [mu]m thick apposing bone, that contained cells varying in size and shape as a function of their location in this cartilaginous layer. Further investigation is required to conclude whether these cells are undergoing further differentiation during development of this graded layer. This study found the interface between bone and the cartilaginous layer to be interdigitated, which may explain why injuries at the bone-tendon interface are comparatively rare. Also, the cartilaginous layer was revealed to be substantially mineralized. A somewhat higher concentration of calcium and phosphorus was observed near the interface with the apposing bone that gradually diminished into the cartilaginous layer. These findings support the four zone description of the bone-tendon interface established by others using histological methods. However, further research is suggested to resolve other questions about the observed sub-micrometer morphologies of the bone-tendon interface. by Willie Mae Reese. S.B. 47 pages eng Massachusetts Institute of Technology MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission. http://dspace.mit.edu/handle/1721.1/7582 Materials Science and Engineering. The natural interface between bone and tendon : SEM observations of the enthesis in an ovine model Scanning electron microscopy observations of the enthesis in an ovine model Thesis application/pdf Publication unknown unknown <Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="bfe22fcd-3181-4711-885e-74a77408b976"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>The natural interface between bone and tendon : SEM observations of the enthesis in an ovine model</Title> <Subtitle>Scanning electron microscopy observations of the enthesis in an ovine model</Subtitle> <PublishedIn> <Publication> </Publication> </PublishedIn> <PublicationDate>2010</PublicationDate> <Authors> <Author> <DisplayName>Reese, Willie Mae</DisplayName> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Massachusetts Institute of Technology</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>http://dspace.mit.edu/handle/1721.1/7582</License> <Keyword>Materials Science and Engineering.</Keyword> <Abstract>The present study investigates the naturally occurring interface between bone and tendon using scanning electron microscopy. The micrographs revealed a cartilaginous layer, 100 to 400 [mu]m thick apposing bone, that contained cells varying in size and shape as a function of their location in this cartilaginous layer. Further investigation is required to conclude whether these cells are undergoing further differentiation during development of this graded layer. This study found the interface between bone and the cartilaginous layer to be interdigitated, which may explain why injuries at the bone-tendon interface are comparatively rare. Also, the cartilaginous layer was revealed to be substantially mineralized. A somewhat higher concentration of calcium and phosphorus was observed near the interface with the apposing bone that gradually diminished into the cartilaginous layer. These findings support the four zone description of the bone-tendon interface established by others using histological methods. However, further research is suggested to resolve other questions about the observed sub-micrometer morphologies of the bone-tendon interface.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication>