2026-09-20T18:48:36Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/1180092022-01-13T07:54:52Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Pierre Azoulay.
Fry, Caroline Viola
Sloan School of Management.
Sloan School of Management
2018-09-17T15:53:39Z
2018-09-17T15:53:39Z
2018
2018
http://hdl.handle.net/1721.1/118009
1051454066
Thesis: S.M. in Management Research, Massachusetts Institute of Technology, Sloan School of Management, 2018.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 21-22).
I investigate the role of country level clinical trial infrastructure on research and development (R&D) levels for neglected tropical diseases concentrated in those countries. Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries.
by Caroline Viola Fry.
S.M. in Management Research
38 pages
eng
Massachusetts Institute of Technology
MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.
http://dspace.mit.edu/handle/1721.1/7582
Sloan School of Management.
If you build it, they will run : the role of clinical trial infrastructure in neglected disease R&D
Role of clinical trial infrastructure in neglected disease Research and Development
Thesis
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<Abstract>I investigate the role of country level clinical trial infrastructure on research and development (R&D) levels for neglected tropical diseases concentrated in those countries. Pre-existing clinical trial infrastructure in a location can affect the cost and time of clinical trials carried out there, thus influence returns on investments for diseases that are located in different places. Using a newly constructed dataset I assess the components that make up a country's clinical trial infrastructure, which varies for countries in different stages of development. Using data on neglected tropical disease global disease burdens and research levels, I find that the level of R&D into diseases concentrated in countries with poorer clinical trial infrastructure is lower than that for diseases concentrated in countries with better infrastructure. This paper suggests a need for further work into the role of research infrastructure in developing countries and its role on innovation outcomes for issues affecting the world's poorest countries.</Abstract>
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