2026-09-19T10:31:49Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/1230732026-06-17T14:44:40Zcom_1721.1_7582com_1721.1_7581col_1721.1_131022
Jeremiah A. Johnson.
Jiang, Yivan.
Massachusetts Institute of Technology. Department of Chemistry.
Massachusetts Institute of Technology. Department of Chemistry
2019-11-22T00:09:59Z
2019-11-22T00:09:59Z
2019
2019
https://hdl.handle.net/1721.1/123073
1127388339
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Chemistry, 2019
Cataloged from PDF version of thesis.
Includes bibliographical references.
Absolute structural control over polymers - in terms of sequence, length, and stereochemistry - is a Holy Grail of polymer science. Inspired by Nature, polymer chemists over the last century have sought new methods and strategies to control these parameters. An inverse relationship exists, however, between the ability to control the primary structure of a macromolecule and the ability to scale the production of the same macromolecule. In this thesis, we describe the application of iterative exponential growth (IEG) toward the scalable synthesis of sequence-defined, unimolecular, chiral polymers. Using this strategy, we have created a wide array of functional molecularly precise polymers of up to 12.1k kDa in molar mass with various side chains for applications in block copolymer phase segregation, lectin binding, and nanoparticle formulations.
by Yivan Jiang.
Ph.D.
Ph.D. Massachusetts Institute of Technology, Department of Chemistry
363 pages
eng
Massachusetts Institute of Technology
MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission.
http://dspace.mit.edu/handle/1721.1/7582
Chemistry.
The synthesis of unimolecular polymers through iterative exponential growth and their applications in block copolymer phase segregation and biological systems
Thesis
application/pdf
2019-11-22T00:09:58Z
Publication
Doctoral
Chem
unknown
unknown
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