2026-09-20T11:02:37Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/1390202022-01-15T03:18:05Zcom_1721.1_7582com_1721.1_7581col_1721.1_131024
Roche, Ellen
Maloney, Charlotte A.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2022-01-14T14:45:04Z
2022-01-14T14:45:04Z
2021-06
2021-06-15T16:17:34.373Z
https://hdl.handle.net/1721.1/139020
Obstructive sleep apnea (OSA) is a common chronic condition which requires ongoing, often lifelong, management. It is a global problem which, left untreated, can result in lower quality of life and general health. Although a wide range of existing treatments exist, their rates of compliance among patients are low. Along with our MIT Catalyst team, I set out to develop and refine a device which prioritized patient comfort with a minimally intrusive design while maintaining safety and efficacy in reducing OSA. I tested multiple parameters within the device to optimize comfort and created a comfort survey to evaluate success. Throughout this process, I simultaneously developed and documented my manufacturing technique for the device, providing a foundation for further tests in patients to measure OSA reduction. In combination with altering the design for comfort, I completed computational simulations in Abaqus to ensure the device did not damage intraoral tissue. This model will allow for team members to quickly test different device configurations prior to manufacturing. Further development of the computational model is necessary to fully mimic the biological tissue.
S.B.
Massachusetts Institute of Technology
In Copyright - Educational Use Permitted
Copyright retained by author(s)
https://rightsstatements.org/page/InC-EDU/1.0/
Design and Manufacturing of a Novel Intraoral Prosthesis for Obstructive Sleep Apnea
Thesis
application/pdf
Bachelor
Bachelor of Science in Mechanical Engineering
Publication
unknown
unknown
<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="b6b27f5a-e4c2-4f0c-8b7e-ff6439a30470">
<Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type>
<Title>Design and Manufacturing of a Novel Intraoral Prosthesis for Obstructive Sleep Apnea</Title>
<PublishedIn>
<Publication>
</Publication>
</PublishedIn>
<PublicationDate>2021-06</PublicationDate>
<Authors>
<Author>
<DisplayName>Maloney, Charlotte A.</DisplayName>
<Affiliation>
<OrgUnit>
</OrgUnit>
</Affiliation>
</Author>
</Authors>
<Editors>
</Editors>
<Publishers>
<Publisher>
<DisplayName>Massachusetts Institute of Technology</DisplayName>
<OrgUnit />
</Publisher>
</Publishers>
<License>https://rightsstatements.org/page/InC-EDU/1.0/</License>
<Abstract>Obstructive sleep apnea (OSA) is a common chronic condition which requires ongoing, often lifelong, management. It is a global problem which, left untreated, can result in lower quality of life and general health. Although a wide range of existing treatments exist, their rates of compliance among patients are low. Along with our MIT Catalyst team, I set out to develop and refine a device which prioritized patient comfort with a minimally intrusive design while maintaining safety and efficacy in reducing OSA. I tested multiple parameters within the device to optimize comfort and created a comfort survey to evaluate success. Throughout this process, I simultaneously developed and documented my manufacturing technique for the device, providing a foundation for further tests in patients to measure OSA reduction. In combination with altering the design for comfort, I completed computational simulations in Abaqus to ensure the device did not damage intraoral tissue. This model will allow for team members to quickly test different device configurations prior to manufacturing. Further development of the computational model is necessary to fully mimic the biological tissue.</Abstract>
<Access xmlns="http://purl.org/coar/access_right"
>
</Access>
</Publication>