2026-09-19T22:20:37Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/179992022-01-13T07:54:29Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Amy E. Keating.
Weston, Kevin T. (Kevin Thomas), 1981-
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
2005-06-02T19:34:15Z
2005-06-02T19:34:15Z
2004
2004
http://hdl.handle.net/1721.1/17999
57203935
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.
Includes bibliographical references (p. 139-143).
In this thesis, we present two computational platforms for future biological research. The first, FNAC, is a flexible programmatic Framework for Network Analysis and Comparison that simplifies many common operations on biological networks. As a demonstration of FNAC, we investigate the properties of several prominent protein function and protein-protein interaction networks. In doing so, we uncover evidence suggesting that a recently-developed technique for annotating proteins may also have substantial value in the computational prediction of protein-protein interactions. Our second computational platform, the Coiled-Coil Database (CCDB), serves as a central and easily queryable repository for information about the coiled coil protein structural motif in a variety of organisms.
by Kevin T. Weston, Jr.
M.Eng.
143 p.
6090612 bytes
6109727 bytes
application/pdf
application/pdf
eng
Massachusetts Institute of Technology
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http://dspace.mit.edu/handle/1721.1/7582
Electrical Engineering and Computer Science.
Network tools forthe analysis and prediction of protein-protein interactions
Thesis
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