<?xml version="1.0" encoding="UTF-8"?><?xml-stylesheet type="text/xsl" href="static/style.xsl"?><OAI-PMH xmlns="http://www.openarchives.org/OAI/2.0/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd"><responseDate>2026-09-20T04:58:34Z</responseDate><request verb="GetRecord" identifier="oai:dspace.mit.edu:1721.1/18002" metadataPrefix="dim">https://dspace.mit.edu/server/oai/request</request><GetRecord><record><header><identifier>oai:dspace.mit.edu:1721.1/18002</identifier><datestamp>2022-01-13T07:54:29Z</datestamp><setSpec>com_1721.1_7582</setSpec><setSpec>com_1721.1_7581</setSpec><setSpec>col_1721.1_131023</setSpec></header><metadata><dim:dim xmlns:dim="http://www.dspace.org/xmlns/dspace/dim" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:doc="http://www.lyncode.com/xoai" xsi:schemaLocation="http://www.dspace.org/xmlns/dspace/dim http://www.dspace.org/schema/dim.xsd">
   <dim:field mdschema="dc" element="contributor" qualifier="advisor" lang="en_US">Luk Van Parijs.</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="author" lang="en_US">Yokoo, Rayka, 1980-</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="other" lang="en_US">Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.</dim:field>
   <dim:field mdschema="dc" element="contributor" qualifier="department">Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science</dim:field>
   <dim:field mdschema="dc" element="date" qualifier="accessioned">2005-06-02T19:34:56Z</dim:field>
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   <dim:field mdschema="dc" element="date" qualifier="copyright" lang="en_US">2004</dim:field>
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   <dim:field mdschema="dc" element="identifier" qualifier="oclc" lang="en_US">57204222</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.</dim:field>
   <dim:field mdschema="dc" element="description" lang="en_US">Includes bibliographical references (leaves 43-44).</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="abstract" lang="en_US">With the development of new experimental technologies, biologists have begun to take a more global view into cell function, approaching its study in a more systematic manner than previously possible. This thesis develops three new tools to perform systems biology studies of cell death in T cells: A modeling program, JDesigner; high throughput T cell apoptosis assays; and an RNAi sequence prediction program. These tools are then applied to a biological and mathematical analysis of Fas signaling pathways in T cells.</dim:field>
   <dim:field mdschema="dc" element="description" qualifier="statementofresponsibility" lang="en_US">by Rayka Yokoo.</dim:field>
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   <dim:field mdschema="dc" element="subject" lang="en_US">Electrical Engineering and Computer Science.</dim:field>
   <dim:field mdschema="dc" element="title" lang="en_US">Biological and computational tools for systems biology : application to Fas signaling pathways in T cells</dim:field>
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   	&lt;Title>Biological and computational tools for systems biology : application to Fas signaling pathways in T cells&lt;/Title>
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   	&lt;Abstract>With the development of new experimental technologies, biologists have begun to take a more global view into cell function, approaching its study in a more systematic manner than previously possible. This thesis develops three new tools to perform systems biology studies of cell death in T cells: A modeling program, JDesigner; high throughput T cell apoptosis assays; and an RNAi sequence prediction program. These tools are then applied to a biological and mathematical analysis of Fas signaling pathways in T cells.&lt;/Abstract>
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