2026-09-19T14:41:49Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/302102022-01-13T07:54:21Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Stephen L. Buchwald.
Dussault, Daemian David, 1973-
Massachusetts Institute of Technology. Dept. of Chemistry.
Massachusetts Institute of Technology. Department of Chemistry
2006-03-24T18:30:33Z
2006-03-24T18:30:33Z
2005
2005
http://hdl.handle.net/1721.1/30210
60696680
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.
Includes bibliographical references (leaves 34-35).
A palladium-catalyzed preparation of 2,3-disubstituted indoles from commercially available and relatively inexpensive reagents, o-chloroacetanilide and internal alkynes, is reported. The system is efficient in delivering 2,3-disubstituted indoles in good to excellent yield with a high level of regioselectivity in most cases. Alkynes with alkyl, aryl, alkenyl, and trialkylsilyl substituents are compatible with this methodology.
by Daemian David Dussault.
S.M.
41, [1] leaves
1537351 bytes
1540037 bytes
application/pdf
application/pdf
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Chemistry.
Synthesis of indoles via palladium-catalyzed annulation of aryl chlorides and internal alkynes
Thesis
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