2026-09-20T01:32:16Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/328672022-01-13T07:54:36Zcom_1721.1_7582com_1721.1_7581col_1721.1_131024
Eric R. Cosman.
Cosman, Niels Johnson
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2006-05-15T20:35:44Z
2006-05-15T20:35:44Z
2005
2005
http://hdl.handle.net/1721.1/32867
62587894
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.
Includes bibliographical references (leaf 41).
Currently there are no of MRI image-based stereotactic apparatus for target determination in the brain of animals. Until now, the only stereotactic devices for directing problems and electrodes in animal brains for neuroscience are based on dental and ear canal fixation and on skull based features which are at best crudely related to brain anatomy. As a result there is no accurate method or apparatus to place a probe into the brain of a research animal. Proposed here is a surgical system to replace these outmoded techniques. The system consists of a MR compatible head frame and a MR localizer designed specifically for the Norway species of rat. This system allows for accurate targeting of structures within the rodent brain and precision placement of electrodes to these structures. This system utilizes the most current MRI imaging technologies available to provide major improvements to quality and reliability in neuroscience data acquisition.
by Niels Johnson Cosman.
S.B.
41 leaves
4532453 bytes
4532304 bytes
application/pdf
application/pdf
eng
Massachusetts Institute of Technology
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http://dspace.mit.edu/handle/1721.1/7582
Mechanical Engineering.
Surgical system for image-based stereotaxy in the rat
Thesis
application/pdf
Publication
unknown
unknown
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<Abstract>Currently there are no of MRI image-based stereotactic apparatus for target determination in the brain of animals. Until now, the only stereotactic devices for directing problems and electrodes in animal brains for neuroscience are based on dental and ear canal fixation and on skull based features which are at best crudely related to brain anatomy. As a result there is no accurate method or apparatus to place a probe into the brain of a research animal. Proposed here is a surgical system to replace these outmoded techniques. The system consists of a MR compatible head frame and a MR localizer designed specifically for the Norway species of rat. This system allows for accurate targeting of structures within the rodent brain and precision placement of electrodes to these structures. This system utilizes the most current MRI imaging technologies available to provide major improvements to quality and reliability in neuroscience data acquisition.</Abstract>
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