2026-09-19T00:22:19Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/333932026-06-06T01:04:21Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
James Galagan and Jill P. Mesirov.
Yu, Tamara H. (Tamara Hui)
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
2006-07-13T15:20:36Z
2006-07-13T15:20:36Z
2004
2004
http://hdl.handle.net/1721.1/33393
62560278
Thesis (M. Eng. and S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2004.
Includes bibliographical references (p. 62-64).
Propelled by advances in sequencing technology, the advent of the genomic era brings the challenge of managing and interpreting massive amount of genomic data. A number of single-genome browsers have been developed for data display. However, they are unsuitable for comparative analysis. We present a dynamic and interactive visualization tool called ComBo that allows users to quickly navigate sequences, browse their similarities in a dot plot format, display sequence annotations in feature maps, and compare annotations in corresponding regions. ComBo allows users to directly control the display. They can compare any two regions in the sequences at any resolution, from an entire chromosome down to the residue level. Users can also retrieve detailed information on any displayed sequence feature or alignment. ComBo can import data from the Calhoun annotation database or flat files. Developed in Java, ComBo has a flexible infrastructure allowing the easy addition of functionality in the future.
by Tamara H. Yu.
M.Eng.
S.B.
64 p.
3322261 bytes
3324858 bytes
application/pdf
application/pdf
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Electrical Engineering and Computer Science.
ComBo : a visualization tool for comparative genomic data
Com Bo : a visualization tool for comparative genomic data
Thesis
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