2026-09-19T06:52:31Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/336172022-01-13T07:54:33Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Francesco Stellacci.
Wu, Diana J
Massachusetts Institute of Technology. Dept. of Materials Science and Engineering.
Massachusetts Institute of Technology. Department of Materials Science and Engineering
2006-07-31T15:17:28Z
2006-07-31T15:17:28Z
2005
2005
http://hdl.handle.net/1721.1/33617
64391159
Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2005.
Includes bibliographical references (p. 73-77).
Self assembling nanostructured nanoparticles represent a new class of synthesized materials with unique functionality. Such monolayer protected metal nanoparticles are capable of resisting protein adsorption, and if utilized as a coating could have broad application in a wide range of industries from consumer products to maritime shipping to medical instruments. The formation of proteic films can adversely affect the performance of materials and is often a limiting factor in device effectiveness. In many instances such as sensors or medical implants, regular cleaning or disposal of the instrument is not a viable option, thus there exists a demand for additional means to prevent nonspecific protein adsorption. Existing protein resistant coating options are still not completely effective, and monolayer protected metal nanoparticle coatings could be a superior means by which to prevent protein adsorption onto material surfaces.
(cont.) This paper explores the commercialization potential of monolayer protected metal nanoparticle coatings for protein resistance; identifying application potential, evaluating potential markets, exploring intellectual property, analyzing the economics of monolayer protected metal nanoparticle synthesis, examining existing technologies, and assessing in depth the medical device industry and entry into the US cardiovascular device market.
by Diana J. Wu.
M.Eng.
77 p.
4035365 bytes
4038509 bytes
application/pdf
application/pdf
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Materials Science and Engineering.
Evaluation of monolayer protected metal nanoparticle technology
Thesis
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