2026-09-19T09:08:34Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/336542026-06-10T15:13:31Zcom_1721.1_7582com_1721.1_7581col_1721.1_131022
Jianshu Cao.
Witkoskie, James B
Massachusetts Institute of Technology. Dept. of Chemistry.
Massachusetts Institute of Technology. Department of Chemistry
2007-02-20T15:30:03Z
2007-02-20T15:30:03Z
2005
2005
http://hdl.handle.net/1721.1/33654
64551507
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2005.
Vita.
Includes bibliographical references (p. 281-311).
Single molecule experiments offer a unique window into the molecular world. This window allows us to distinguish the behaviors of individual molecules from the behavior of bulk by observing rare events and heterogeneity in the dynamics. This thesis discusses both models for single molecule experiments, including the stretching of DNA in hydrodynamic flows and the diffusion of tracer particles in heterogeneous environments, and methods to analyze single molecule data to allow determination of properties and models for single molecule experiments. These methods of analysis are based on combining information theory and Bayesian methods with physical insight and are applied to several experimental situations.
by James B. Witkoskie.
Ph.D.
313, 3 p.
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Chemistry.
Modeling and analysis of single-molecule experiments
Thesis
application/pdf
Publication
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