2026-09-19T04:28:44Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/339072022-01-13T07:54:36Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Roger D. Kamm and Mohammad R. Kaazempur Mofrad.
Zhu, Ting F. (Ting Fredrick)
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2006-08-25T18:55:43Z
2006-08-25T18:55:43Z
2005
2005
http://hdl.handle.net/1721.1/33907
66910312
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2005.
Includes bibliographical references (leaves 57-59).
A numerical method has been developed to estimate the mechanical properties of atherosclerotic plaques by combining genetic algorithm with finite element methods. Plaque images derived from optical coherence tomography were employed to construct finite element models which were subsequently used in conjunction with a genetic algorithm to determine the parameters in a nonlinear constitutive model. A new multi-frame scheme is introduced to better perform the estimation on a nonlinear mechanical model and reduce the effects of noise. Results show while it is feasible to estimate the nonlinear mechanical properties of plaque, the accuracy can depend on various factors, especially the noise. KEY woRDS: FEM, atherosclerotic plaques, parameter estimation, Mooney-Rivlin model, optical coherence tomography, image noise.
by Ting F. Zhu.
S.M.
91 leaves
3195834 bytes
3199589 bytes
application/pdf
application/pdf
eng
Massachusetts Institute of Technology
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http://dspace.mit.edu/handle/1721.1/7582
Mechanical Engineering.
Estimation of nonlinear mechanical properties of atherosclerotic plaques
Thesis
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