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Ian W. Hunter. Brayanov, Jordan, 1981- Massachusetts Institute of Technology. Dept. of Mechanical Engineering. Massachusetts Institute of Technology. Department of Mechanical Engineering 2007-01-10T17:01:00Z 2007-01-10T17:01:00Z 2006 2006 http://hdl.handle.net/1721.1/35677 76838137 Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2006. Includes bibliographical references (leaves 115-117). The rapid development of needle-free injection systems demands better and faster imaging systems, capable of imaging the transient and steady state response of an injection into real tissue. X-ray radiography, x-ray microscopy, and computerized tomography (CT) were identified as the most appropriate imaging techniques used for non-invasive imaging of opaque objects and an instrument was constructed, utilizing all of those techniques. The instrument was capable of producing x-ray radiographies with native resolution of less than 30 [mu]m, frame rate of 32 frames per second and a field of view of 30 mm by 40 mm. Using magnifying cone-beam x-ray source the ultimate resolution of the system exceeded 5 [mu]m, while maintaining image sharpness and clarity. Digital image reconstruction techniques, based on the inverse Radon transformation and the Fourier slice theorem were used to regenerate conventional CT images as well as contrast volumetric 3D images of the internal structures of opaque objects. This paper presents the design and development of the 3D x-ray microscope together with experimental results obtained during the calibration and initial testing of the instrument. by Jordan B. Brayanov. S.M. 133 leaves 3559606 bytes 3562544 bytes application/pdf application/pdf eng Massachusetts Institute of Technology CDROM contains CAD models primarily in .par format; Documentation in .pdf format; Experimental data and instrument pictures in various formats; Movies in .avi format; various software complete with .exe files; and Thesis--final version in .doc format. M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 Mechanical Engineering. Design and development of a 3D X-ray microscope Design and development of a three-dimensional X-ray microscope Thesis application/pdf false Publication unknown unknown <Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="520ad23d-b0ca-432e-918b-412e6a218fc3"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Design and development of a 3D X-ray microscope</Title> <Subtitle>Design and development of a three-dimensional X-ray microscope</Subtitle> <PublishedIn> <Publication> </Publication> </PublishedIn> <PublicationDate>2006</PublicationDate> <Authors> <Author> <DisplayName>Brayanov, Jordan, 1981-</DisplayName> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Massachusetts Institute of Technology</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>http://dspace.mit.edu/handle/1721.1/7582</License> <Keyword>Mechanical Engineering.</Keyword> <Abstract>The rapid development of needle-free injection systems demands better and faster imaging systems, capable of imaging the transient and steady state response of an injection into real tissue. X-ray radiography, x-ray microscopy, and computerized tomography (CT) were identified as the most appropriate imaging techniques used for non-invasive imaging of opaque objects and an instrument was constructed, utilizing all of those techniques. The instrument was capable of producing x-ray radiographies with native resolution of less than 30 [mu]m, frame rate of 32 frames per second and a field of view of 30 mm by 40 mm. Using magnifying cone-beam x-ray source the ultimate resolution of the system exceeded 5 [mu]m, while maintaining image sharpness and clarity. Digital image reconstruction techniques, based on the inverse Radon transformation and the Fourier slice theorem were used to regenerate conventional CT images as well as contrast volumetric 3D images of the internal structures of opaque objects. This paper presents the design and development of the 3D x-ray microscope together with experimental results obtained during the calibration and initial testing of the instrument.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication>