2026-09-19T08:01:47Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/372012022-01-13T07:54:29Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023col_1721.1_131024
Ian W. Hunter.
Hemond, Brian D. (Brian David Thomson)
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
2007-04-20T15:48:57Z
2007-04-20T15:48:57Z
2006
2004
http://hdl.handle.net/1721.1/37201
78920897
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, June 2004; and, (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2006.
Includes bibliographical references (leaves 89-90).
The advantages of delivering injections via needle-free methods are numerous. However, conventional methods for needle-free injection lack sufficient control over depth of penetration and shape of injection. Thus, a needle-free injector was designed, constructed, and tested, using a controllable linear Lorentz-force actuator. This actuator allows rapid control of the injection pressure during injections. Using this device, precise control over delivery parameters can be achieved. In addition, several portable power systems for this injector were developed, allowing the energy-intensive needle-free injector to be used in the field. The injector design was tested for repeatability and use for both in-vitro and in-vivo testing on murine tissue using a bacterial collagenase.
by Brian D. Hemond.
M.Eng.
S.B.
145 leaves
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Electrical Engineering and Computer Science.
A Lorentz-force actuated controllable needle-free drug delivery system
Thesis
application/pdf
false
Publication
unknown
unknown
<Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="3800b0c1-e25c-4026-9b1c-7f3349018013">
<Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type>
<Language>eng</Language>
<Title>A Lorentz-force actuated controllable needle-free drug delivery system</Title>
<PublishedIn>
<Publication>
</Publication>
</PublishedIn>
<PublicationDate>2004</PublicationDate>
<Authors>
<Author>
<DisplayName>Hemond, Brian D. (Brian David Thomson)</DisplayName>
<Affiliation>
<OrgUnit>
</OrgUnit>
</Affiliation>
</Author>
</Authors>
<Editors>
</Editors>
<Publishers>
<Publisher>
<DisplayName>Massachusetts Institute of Technology</DisplayName>
<OrgUnit />
</Publisher>
</Publishers>
<License>http://dspace.mit.edu/handle/1721.1/7582</License>
<Keyword>Electrical Engineering and Computer Science.</Keyword>
<Abstract>The advantages of delivering injections via needle-free methods are numerous. However, conventional methods for needle-free injection lack sufficient control over depth of penetration and shape of injection. Thus, a needle-free injector was designed, constructed, and tested, using a controllable linear Lorentz-force actuator. This actuator allows rapid control of the injection pressure during injections. Using this device, precise control over delivery parameters can be achieved. In addition, several portable power systems for this injector were developed, allowing the energy-intensive needle-free injector to be used in the field. The injector design was tested for repeatability and use for both in-vitro and in-vivo testing on murine tissue using a bacterial collagenase.</Abstract>
<Access xmlns="http://purl.org/coar/access_right"
>
</Access>
</Publication>