2026-09-18T23:41:17Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/379462022-01-13T07:54:29Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Joel Voldman.
Lee, Hsu-Yi
Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science.
Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
2007-07-18T13:13:54Z
2007-07-18T13:13:54Z
2006
2006
http://hdl.handle.net/1721.1/37946
144579958
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006.
Includes bibliographical references (leaves 69-71).
Dielectrophoretic (DEP) force, generated by interdigitated electrodes (IDEs), has been utilized to capture bio-particles for microfluidic concentration. However, due to the localized DEP force, DEP-based ,/ -concentrators usually have shallow channels and thus are operated under low flow rates. In this thesis, we propose a mixer-enhanced DEP-based concentrator which can be operate under high flow rates (-200 /l/min) with 20 Vpp applied voltage. In particular, the optimal geometries of micromixers for the device are investigated and determined by simulations and experiments. The optimal micromixer-enhanced concentrator exhibits up to 1.5 x improvement in trapping efficiency as compared to a concentrator without mixers.
by Hsu-Yi Lee.
S.M.
71 leaves
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Electrical Engineering and Computer Science.
Optimizing mixer geometries for dielectrophoretic micro-concentrators
Optimizing mixer geometries for DEP micro-concentrators
Thesis
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<Abstract>Dielectrophoretic (DEP) force, generated by interdigitated electrodes (IDEs), has been utilized to capture bio-particles for microfluidic concentration. However, due to the localized DEP force, DEP-based ,/ -concentrators usually have shallow channels and thus are operated under low flow rates. In this thesis, we propose a mixer-enhanced DEP-based concentrator which can be operate under high flow rates (-200 /l/min) with 20 Vpp applied voltage. In particular, the optimal geometries of micromixers for the device are investigated and determined by simulations and experiments. The optimal micromixer-enhanced concentrator exhibits up to 1.5 x improvement in trapping efficiency as compared to a concentrator without mixers.</Abstract>
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