2026-09-18T22:05:16Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/398862022-01-13T07:54:36Zcom_1721.1_7582com_1721.1_7581col_1721.1_131023
Daniel E. Ehrlich and Anette Hosoi.
Lin, Tony An-tong
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2008-01-10T15:51:42Z
2008-01-10T15:51:42Z
2007
2007
http://hdl.handle.net/1721.1/39886
182540246
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.
Includes bibliographical references (p. 107-109).
The development of microfluidic devices has enabled precision control of nanoliter-scale environments and reactions. Vertical hydrodynamic focusing is one possible way to improve the optical performance of these devices while maintaining precision control. Vertical hydrodynamic focusing was studied through the use of computation fluid dynamics (ADINA) and experimental testing. It was found that the nonlinear effects of flow rate and geometry on the layering profile could be used to tune and correct the flow. A syringe pump-driven microfluidic device was fabricated out of isotropically etched and bonded glass plates and fluorescent confocal microscopy was used to verify computational models.
by Tony An-tong Lin.
S.M.
109 p.
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Mechanical Engineering.
Vertical hydrodynamic focusing in an isotropically etched glass microfluidic device
Thesis
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