2026-09-19T05:35:50Zhttps://dspace.mit.edu/server/oai/requestoai:dspace.mit.edu:1721.1/404162022-01-13T07:54:36Zcom_1721.1_7582com_1721.1_7581col_1721.1_131024
Myron Spector.
Chan, Jenny K. (Jenny Kamjun)
Massachusetts Institute of Technology. Dept. of Mechanical Engineering.
Massachusetts Institute of Technology. Department of Mechanical Engineering
2008-02-27T22:22:57Z
2008-02-27T22:22:57Z
2007
2007
http://hdl.handle.net/1721.1/40416
191698827
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.
Includes bibliographical references (p. 25).
This study was performed to determine whether the particle size of the starting collagen powder or the material of molds used during freeze-drying had effects on the scaffold pore structure. Collagen particles were separated by size prior to slurry making using a sieve with 1000 [mu]m openings, and scaffolds were made using both metal pans and polysulfone trays, two commonly used molds. The mean and variation of pore diameter and interconnectivity of freeze-dried scaffolds were compared to determine the relationship between particle size or mold material and the resulting pore diameter, for a specific same freeze-drying condition (viz., temperature). Knowing these relationships will permit a better control of pore size during fabrication, allowing researchers to design scaffolds with greater predictability and specificity.
by Jenny K. Chan.
S.B.
25 p.
eng
Massachusetts Institute of Technology
M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission.
http://dspace.mit.edu/handle/1721.1/7582
Mechanical Engineering.
The effects of particle size of collagen and mold material on the pore structure of freeze-dried collagen-GAG scaffolds
Thesis
application/pdf
Publication
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unknown
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