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William J. Long. You, Shu-Chyng Massachusetts Institute of Technology. Dept. of Electrical Engineering and Computer Science. Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science 2008-09-03T14:39:20Z 2008-09-03T14:39:20Z 2006 2006 http://hdl.handle.net/1721.1/42122 227037473 Thesis (M. Eng.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2006. Includes bibliographical references (p. 81-83). With the rapid advancement of computational data analysis tools, medical informatics has emerged as a discipline that explores the use of medical information in clinical practice. It searches for ways to effectively integrate as much information as is available to physicians when they make clinical decisions and represent the information in the most intelligent way possible. As part of an overall effort to develop a program that assists physicians in making clinical decisions on patients with heart disease, we developed a model for predicting therapy effects in heart disease using signal flow analysis that describes constraint relations among physiological parameters. In order to accurately describe and predict the therapy effects on a patient in heart failure, the model needs to be tested and analyzed with real-life patient data including any cardiovascular parameters measurable in the patient. This thesis will present methods for extracting hemodynamic relations and drug effects from patients in the intensive care unit. In this thesis, we propose to test our hypothesis that significant relationships between hemodynamic parameters can be derived from certain classifications of patients and sectioning of hospital stays, and explore the effects of drugs on patients with different sets of diseases. by Chu-Chyng You. M.Eng. 83 p. eng Massachusetts Institute of Technology M.I.T. theses are protected by copyright. They may be viewed from this source for any purpose, but reproduction or distribution in any format is prohibited without written permission. See provided URL for inquiries about permission. http://dspace.mit.edu/handle/1721.1/7582 Electrical Engineering and Computer Science. Validating the therapy prediction model through a breakdown analysis on ICU patient medical records Thesis application/pdf false Publication unknown unknown <Publication xmlns="https://www.openaire.eu/cerif-profile/1.1/" id="cec4deb0-bf6c-4594-836e-cc58e704efd4"> <Type xmlns="https://www.openaire.eu/cerif-profile/vocab/COAR_Publication_Types">http://purl.org/coar/resource_type/c_1843</Type> <Language>eng</Language> <Title>Validating the therapy prediction model through a breakdown analysis on ICU patient medical records</Title> <PublishedIn> <Publication> </Publication> </PublishedIn> <PublicationDate>2006</PublicationDate> <Authors> <Author> <DisplayName>You, Shu-Chyng</DisplayName> <Affiliation> <OrgUnit> </OrgUnit> </Affiliation> </Author> </Authors> <Editors> </Editors> <Publishers> <Publisher> <DisplayName>Massachusetts Institute of Technology</DisplayName> <OrgUnit /> </Publisher> </Publishers> <License>http://dspace.mit.edu/handle/1721.1/7582</License> <Keyword>Electrical Engineering and Computer Science.</Keyword> <Abstract>With the rapid advancement of computational data analysis tools, medical informatics has emerged as a discipline that explores the use of medical information in clinical practice. It searches for ways to effectively integrate as much information as is available to physicians when they make clinical decisions and represent the information in the most intelligent way possible. As part of an overall effort to develop a program that assists physicians in making clinical decisions on patients with heart disease, we developed a model for predicting therapy effects in heart disease using signal flow analysis that describes constraint relations among physiological parameters. In order to accurately describe and predict the therapy effects on a patient in heart failure, the model needs to be tested and analyzed with real-life patient data including any cardiovascular parameters measurable in the patient. This thesis will present methods for extracting hemodynamic relations and drug effects from patients in the intensive care unit. In this thesis, we propose to test our hypothesis that significant relationships between hemodynamic parameters can be derived from certain classifications of patients and sectioning of hospital stays, and explore the effects of drugs on patients with different sets of diseases.</Abstract> <Access xmlns="http://purl.org/coar/access_right" > </Access> </Publication>